Institute of Psychophysiology and Rehabilitation, Lithuanian University of Health Sciences, Palanga, Lithuania.
Gen Hosp Psychiatry. 2011 Sep-Oct;33(5):527-9. doi: 10.1016/j.genhosppsych.2011.06.009. Epub 2011 Aug 17.
Self-rating instruments for depression include questions targeting fatigue, which is a common symptom of coronary artery disease (CAD) patients. We evaluated if specific fatigue-related questions in self-reported instruments of depression bias an association between fatigue and depression in CAD patients.
A total of 1470 CAD patients attending cardiac rehabilitation program were evaluated for fatigue using the Multidimensional Fatigue Inventory (MFI-20) and for symptoms of depression using the depression subscale of the Hospital Anxiety and Depression scale (HADS-D) and the Beck Depression Inventory-II (BDI-II).
There was moderate correlation in MFI-20 scores vs. HADS-D scores and in MFI-20 scores vs. BDI-II scores, with stronger association in patients with less severe heart failure when compared to patients with more severe heart failure. Removal of questions targeting fatigue from the HADS-D and the BDI-II did not significantly change the association.
Fatigue-related items should not be removed from the HADS-D and the BDI-II when evaluating CAD patients for depressive symptoms.
抑郁自评量表包括针对疲劳的问题，而疲劳是冠状动脉疾病（CAD）患者的常见症状。我们评估了抑郁自评量表中特定的与疲劳相关的问题是否会影响 CAD 患者中疲劳与抑郁之间的关联。
共有 1470 名接受心脏康复计划的 CAD 患者使用多维疲劳量表（MFI-20）评估疲劳，使用医院焦虑和抑郁量表（HADS-D）的抑郁分量表和贝克抑郁量表-II（BDI-II）评估抑郁症状。
MFI-20 评分与 HADS-D 评分和 MFI-20 评分与 BDI-II 评分之间存在中度相关性，与心力衰竭程度较轻的患者相比，心力衰竭程度较重的患者相关性更强。从 HADS-D 和 BDI-II 中删除针对疲劳的问题并不会显著改变这种关联。
在评估 CAD 患者的抑郁症状时，不应从 HADS-D 和 BDI-II 中删除与疲劳相关的项目。
