Boothe D M
Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine, Texas A&M University, College Station 77843-4466.
J Am Vet Med Assoc. 1990 Apr 15;196(8):1297-305.
This is the first of a 4-part series concerning drug therapy in cats. In this article, factors that may increase the incidence of type-A adverse drug reactions in cats are discussed. Factors related to species and age differences, drug interactions, and the effects of disease are emphasized. Those that tend to be unique to cats, such as species-induced differences in drug disposition, are described in detail when sufficient information was available from the literature. General recommendations regarding drug administration are made, which will facilitate the implementation of rational drug therapy in cats, thus reducing the incidence of adverse reactions.
这是关于猫用药治疗的四部分系列文章中的第一篇。本文讨论了可能增加猫A型药物不良反应发生率的因素。重点强调了与物种和年龄差异、药物相互作用以及疾病影响相关的因素。当文献中有足够信息时，会详细描述那些猫特有的因素，如物种引起的药物处置差异。文中还给出了关于药物给药的一般建议，这将有助于在猫中实施合理的药物治疗，从而降低不良反应的发生率。
