卡泊芬净治疗慢性肺球孢子菌病。

Treatment of chronic pulmonary blastomycosis with caspofungin.

机构信息

University of Montréal, Montréal, Canada.

Department of Pneumology, Sacré-Coeur Hospital, Montréal, Canada.

出版信息

J Med Microbiol. 2011 Dec;60(Pt 12):1875-1878. doi: 10.1099/jmm.0.036103-0. Epub 2011 Aug 18.

DOI:10.1099/jmm.0.036103-0

PMID:21852530

Abstract

Current practice guidelines recommend that pulmonary blastomycosis be treated with antifungal agents such as amphotericin B and itraconazole. Echinocandins are not recommended because of poor in vitro activity against Blastomyces dermatitidis and lack of supporting clinical data. We report a case of chronic pulmonary blastomycosis treated successfully with caspofungin.

摘要

目前的实践指南建议使用抗真菌药物治疗肺球孢子菌病，如两性霉素 B 和伊曲康唑。由于棘白菌素类药物对皮炎球孢子菌的体外活性差且缺乏支持的临床数据，因此不建议使用。我们报告了一例成功用卡泊芬净治疗的慢性肺球孢子菌病。