Institute of Imaging Science, Vanderbilt University, Nashville, TN, USA.
Phys Med Biol. 2011 Sep 21;56(18):5877-88. doi: 10.1088/0031-9155/56/18/007. Epub 2011 Aug 18.
We present an initial evaluation of a mechanically cooled, high-purity germanium double-sided strip detector as a potential gamma camera for small-animal SPECT. It is 90 mm in diameter and 10 mm thick with two sets of 16 orthogonal strips that have a 4.5 mm width with a 5 mm pitch. We found an energy resolution of 0.96% at 140 keV, an intrinsic efficiency of 43.3% at 122 keV and a FWHM spatial resolution of approximately 1.5 mm. We demonstrated depth-of-interaction estimation capability through comparison of pinhole acquisitions with a point source on and off axes. Finally, a flood-corrected flood image exhibited a strip-level uniformity of less than 1%. This high-purity germanium offers many desirable properties for small-animal SPECT.
我们对一种机械冷却的高纯锗双面条探测器进行了初步评估，该探测器有望成为一种用于小动物 SPECT 的伽马相机。它的直径为 90 毫米，厚度为 10 毫米，有两组 16 个正交条，每条宽 4.5 毫米，节距为 5 毫米。我们发现，在 140keV 下能量分辨率为 0.96%，在 122keV 下固有效率为 43.3%，FWHM 空间分辨率约为 1.5 毫米。我们通过对比针孔采集和离轴点源的采集，证明了该探测器具有探测深度的能力。最后，经洪水校正的洪水图像显示，条带级的均匀性小于 1%。这种高纯锗为小动物 SPECT 提供了许多理想的特性。
