Rollason T P, Byrne P, Williams A
Department of Pathology, University of Birmingham Medical School, Edgbaston, England.
J Clin Pathol. 1990 Mar;43(3):224-9. doi: 10.1136/jcp.43.3.224.
Eleven classic benign "fibroepithelial polyps" of the vagina were examined using a panel of immunocytochemical agents. Two were also examined electron microscopically. In all cases the stellate and multinucleate stromal cells characteristic of these lesions stained strongly for desmin, indicating muscle intermediate filament production. In common with uterine fibroleiomyomata, numerous mast cells were also often seen. Myoglobin staining was negative. Electron microscopical examination confirmed that the stromal cells contained abundant thin filaments with focal densities and also showed the ultrastructural features usually associated with myofibroblasts. It is concluded that these tumours would be better designated polypoid myofibroblastomas in view of the above findings.
使用一组免疫细胞化学试剂对11例经典的阴道良性“纤维上皮息肉”进行了检查。其中2例还进行了电子显微镜检查。在所有病例中，这些病变特征性的星状和多核基质细胞结蛋白染色强烈，表明有肌中间丝生成。与子宫纤维平滑肌瘤一样，也经常可见大量肥大细胞。肌红蛋白染色为阴性。电子显微镜检查证实，基质细胞含有丰富的有局灶性致密物质的细肌丝，并且还显示出通常与肌成纤维细胞相关的超微结构特征。鉴于上述发现，得出结论认为这些肿瘤最好命名为息肉状肌成纤维细胞瘤。
