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爱尔兰艾滋病毒阳性队列中成功进行器官移植的出现。

The advent of successful organ transplantation in the Irish HIV positive cohort.

机构信息

Department of Genitourinary Medicine and Infectious Diseases, St. James's Hospital, James's Street, Dublin 8, Ireland.

出版信息

Ir J Med Sci. 2012 Mar;181(1):49-52. doi: 10.1007/s11845-011-0746-9. Epub 2011 Aug 19.

Abstract

BACKGROUND

Liver disease is an increasing cause of morbidity and mortality in Human immunodeficiency virus (HIV) positive patients.

AIM

To describe the first cases of organ transplantation in HIV positive patients in Ireland.

METHOD

We report the Irish patients with HIV who received liver transplantation and performed a chart review.

RESULT

Two patients received liver transplantation for end stage liver disease caused by Hepatitis C, with survival at 2 years of 100%.

CONCLUSION

Liver transplantation is a feasible treatment for patients with HIV and end stage liver disease. The success of transplantation in the HIV positive population should encourage the provision of other medical and surgical interventions previously not offered to patients with HIV.

摘要

背景

肝脏疾病是导致人类免疫缺陷病毒(HIV)阳性患者发病率和死亡率上升的一个因素。

目的

描述爱尔兰首例 HIV 阳性患者接受器官移植的案例。

方法

我们报告了在爱尔兰接受肝移植的 HIV 患者,并进行了病历回顾。

结果

两名患者因丙型肝炎导致终末期肝病接受了肝移植,2 年生存率为 100%。

结论

肝移植是治疗 HIV 合并终末期肝病患者的一种可行方法。HIV 阳性人群移植的成功应该鼓励为以前未向 HIV 患者提供的其他医疗和外科干预措施提供支持。

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