Bergman Marković Biserka, Vrdoljak Davorka, Kranjcević Ksenija, Vucak Jasna, Kern Josipa, Bielen Ivan, Ivezić Lalić Dragica, Katić Milica, Reiner Zeljko
Department of Family Medicine, University of Split School of Medicine, Soltanska 2, 21000 Split, Croatia.
Croat Med J. 2011 Aug 15;52(4):566-75. doi: 10.3325/cmj.2011.52.566.
To compare the distribution of cardiovascular disease (CVD) factors between continental and Mediterranean areas and urban and rural areas of Croatia, as well as to investigate the differences in achieving treatment goals by the general practitioners (GP) in different settings.
A multicenter prospective study was performed on 2467 participants of both sexes ≥40 years old, who visited for any reason 59 general practices covering the whole area of Croatia (May-July 2008). The study was a part of the Cardiovascular Risk and Intervention Study in Croatia-family medicine (CRISIC-fm) study. Patients were interviewed using a 140-item questionnaire on socio-demographics and CVD risk factors. We measured body mass index (BMI) and waist circumference and determined biochemical variables including blood pressure, total, high-density lipoprotein-, and low-density lipoprotein-cholesterol, triglycerides, glycemia, and uric acid.
Participants from continental rural areas had significantly higher systolic and diastolic blood pressure (P<0.001), obesity (P=0.001), increased waist circumference (P<0.001), and more intense physical activity (P=0.020). Participants from coastal rural areas had higher HDL-cholesterol, participants from continental rural and coastal urban areas had higher LDL-cholesterol, and participants from rural continental had significantly higher BMI and waist circumference.
Prevalence of CVD risk factors in Croatian population is high. Greater burden of risk factors in continental region and rural areas may be partly explained by lifestyle differences.
比较克罗地亚大陆地区与地中海地区以及城乡之间心血管疾病（CVD）因素的分布情况，并调查不同环境下全科医生（GP）在实现治疗目标方面的差异。
对2467名年龄≥40岁的男女参与者进行了一项多中心前瞻性研究，这些参与者因任何原因就诊于覆盖克罗地亚全境的59家全科诊所（2008年5月至7月）。该研究是克罗地亚家庭医学心血管风险与干预研究（CRISIC-fm）的一部分。使用一份包含140个条目的问卷对患者进行社会人口统计学和CVD危险因素方面的访谈。我们测量了体重指数（BMI）和腰围，并测定了包括血压、总胆固醇、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇、甘油三酯、血糖和尿酸在内的生化变量。
来自大陆农村地区的参与者收缩压和舒张压显著更高（P<0.001），肥胖率更高（P=0.001），腰围增加（P<0.001），且体力活动更剧烈（P=0.020）。来自沿海农村地区的参与者高密度脂蛋白胆固醇更高，来自大陆农村和沿海城市地区的参与者低密度脂蛋白胆固醇更高，来自大陆农村的参与者BMI和腰围显著更高。
克罗地亚人群中CVD危险因素的患病率较高。大陆地区和农村地区危险因素负担较重可能部分归因于生活方式的差异。
