Guyot M, Doutremepuich C
Laboratoire de Pharmacie Galénique, Université de Bordeaux II.
J Pharm Belg. 1990 Jan-Feb;45(1):20-8.
To palliate certain drawbacks in blood transfusion, some preparations are studied as oxygen-transporting erythrocytic substitutes; these are preparations of a biological origin such as hemoglobin solutions, or synthetic preparations such as fluorocarbon emulsions. Part 1 studies solutions of purified, pyridoxylated and/or polymerized hemoglobin of human or animal origin.
为缓解输血中的某些缺点,人们研究了一些作为氧输送红细胞替代物的制剂;这些制剂有生物来源的,如血红蛋白溶液,也有合成制剂,如氟碳乳剂。第1部分研究人源或动物源的纯化、吡哆醛化和/或聚合血红蛋白溶液。