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[巴雷特食管的病理解剖学]

[Pathologic anatomy of Barrett's esophagus].

作者信息

Zaĭrat'iants O V, Maev I V, Smol'iannikova V A, Movtaeva P R

出版信息

Arkh Patol. 2011 May-Jun;73(3):21-6.

PMID:21853919
Abstract

It is most substantiated to define Barrett's esophagus as intestinal metaplasia of esophageal cardiac mucosa irrespective of its association with the endoscopically detected esophageogastric junction, which develops as a result of gastroesophageal reflux. There is a need for further investigations of the specific features of the cardiac-type mucosa. During endoscopic study, it is important to be alert when identifying short and ultrashort Barrett's esophagus and to sample sufficient biopsy material. A pathologist must differentiate three major types of the cylindrical epithelium of the esophagus: cardiac, acid-producing cardiac, and intestinal metaplasia, by diagnosing Barrett's esophagus in the latter case. Patients with the esophageal cardiac mucosa should be referred to as a risk group for its development.

摘要

将巴雷特食管定义为食管贲门黏膜的肠化生,而不论其与内镜检查发现的食管胃交界的关系如何,这种化生是胃食管反流的结果,这一定义最有依据。有必要进一步研究贲门型黏膜的具体特征。在内镜检查过程中,识别短段和超短段巴雷特食管并采集足够的活检材料时,保持警惕很重要。病理学家必须区分食管柱状上皮的三种主要类型:贲门型、产酸贲门型和肠化生,在后一种情况下诊断为巴雷特食管。食管贲门黏膜患者应被视为其发生的风险人群。

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1
[Pathologic anatomy of Barrett's esophagus].[巴雷特食管的病理解剖学]
Arkh Patol. 2011 May-Jun;73(3):21-6.
2
Pathophysiology of Barrett's esophagus.巴雷特食管的病理生理学
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3
[The influence of Barrett's esophagus on the clinical signs and postoperative results of GERD].[巴雷特食管对胃食管反流病临床症状及术后结果的影响]
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Clinical, endoscopic, and functional studies in 408 patients with Barrett's esophagus, compared to 174 cases of intestinal metaplasia of the cardia.对408例巴雷特食管患者进行了临床、内镜及功能研究,并与174例贲门肠化生病例进行了比较。
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The prevalence of intestinal metaplasia in patients with and without peptic strictures.有和没有消化性狭窄的患者中肠化生的患病率。
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Helicobacter pylori infection, not gastroesophageal reflux, is the major cause of inflammation and intestinal metaplasia of gastric cardiac mucosa.幽门螺杆菌感染而非胃食管反流,是贲门胃黏膜炎症和肠化生的主要原因。
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[Association between symptomatic gastroesophageal reflux and Barrett's esophagus].[症状性胃食管反流与巴雷特食管之间的关联]
Rev Gastroenterol Mex. 2005 Jan-Mar;70(1):14-9.
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Proinflammatory cytokine and nuclear factor kappa-B expression along the inflammation-metaplasia-dysplasia-adenocarcinoma sequence in the esophagus.食管中炎症-化生-发育异常-腺癌序列中促炎细胞因子和核因子κB的表达
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Short and ultrashort Barrett's esophagus--what does it mean?短段及超短段巴雷特食管——这意味着什么?
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