Zaĭrat'iants O V, Maev I V, Smol'iannikova V A, Movtaeva P R
Arkh Patol. 2011 May-Jun;73(3):21-6.
It is most substantiated to define Barrett's esophagus as intestinal metaplasia of esophageal cardiac mucosa irrespective of its association with the endoscopically detected esophageogastric junction, which develops as a result of gastroesophageal reflux. There is a need for further investigations of the specific features of the cardiac-type mucosa. During endoscopic study, it is important to be alert when identifying short and ultrashort Barrett's esophagus and to sample sufficient biopsy material. A pathologist must differentiate three major types of the cylindrical epithelium of the esophagus: cardiac, acid-producing cardiac, and intestinal metaplasia, by diagnosing Barrett's esophagus in the latter case. Patients with the esophageal cardiac mucosa should be referred to as a risk group for its development.
将巴雷特食管定义为食管贲门黏膜的肠化生,而不论其与内镜检查发现的食管胃交界的关系如何,这种化生是胃食管反流的结果,这一定义最有依据。有必要进一步研究贲门型黏膜的具体特征。在内镜检查过程中,识别短段和超短段巴雷特食管并采集足够的活检材料时,保持警惕很重要。病理学家必须区分食管柱状上皮的三种主要类型:贲门型、产酸贲门型和肠化生,在后一种情况下诊断为巴雷特食管。食管贲门黏膜患者应被视为其发生的风险人群。