Solana M J, López-Herce J, Urbano J, Mencía S, del Castillo J, Bellón J M
Servicio de Cuidados Intensivos Pediátricos, Hospital General Universitario Gregorio Marañón, Universidad Complutense, Madrid, España.
An Pediatr (Barc). 2012 Jan;76(1):11-5. doi: 10.1016/j.anpedi.2011.06.007. Epub 2011 Aug 19.
To ascertain whether a spirometer can measure tidal volume (TV) during high frequency oscillatory ventilation (HFOV) and high frequency jet ventilation (HFJV), and to analyse the effect of changes in ventilator settings.
The study was performed with paediatric porcine lung models submitted to HFOV with a Sensormedics 3100 ventilator and HFJV with a Paravent Pat(e)(R) ventilator connected to a D-Fend spirometer. Programmed frequency, amplitude, and mean airway pressure (MAP) were changed in the ventilator, and TV and pressures were recorded using the spirometer.
The spirometer measured TV in the paediatric lung models and piglets, but could not measure TV less than 8 ml, when the pressure amplitude was higher than 55 cmH(2)O or the MAP was higher than 30 cmH(2)O. With HFOV there was a correlation between amplitude and tidal volume, and a positive correlation between pressure and TV with HFJV. With both respirators there was a negative correlation between frequency and TV.
The D-Fend spirometer can measure tidal volume and pressure during HFOV and HFJV. However, it does not work with volumes lower than 8 ml, and high amplitude or mean airway pressure.
确定肺量计能否在高频振荡通气（HFOV）和高频喷射通气（HFJV）期间测量潮气量（TV），并分析呼吸机设置变化的影响。
本研究使用连接到D-Fend肺量计的Sensormedics 3100呼吸机对小儿猪肺模型进行HFOV，并使用Paravent Pat(e)(R)呼吸机进行HFJV。在呼吸机中改变编程频率、振幅和平均气道压（MAP），并使用肺量计记录TV和压力。
肺量计可测量小儿肺模型和仔猪的TV，但当压力振幅高于55 cmH₂O或MAP高于30 cmH₂O时，无法测量小于8 ml的TV。在HFOV中，振幅与潮气量之间存在相关性，在HFJV中，压力与TV之间存在正相关。使用这两种呼吸机时，频率与TV之间均存在负相关。
D-Fend肺量计可在HFOV和HFJV期间测量潮气量和压力。然而，它不适用于低于8 ml的容量以及高振幅或平均气道压情况。
