Pokrovskiĭ A V, Varava B N, Zotikov A E, Iudin V I
Ter Arkh. 1990;62(1):43-6.
The authors summarize the first experience gained with the use of pulse therapy with cyclophosphamide and 6-methylprednisolone in 18 patients with acute and subacute nonspecific aortoarteritis. Remission attained in 16 patients was attended by a decrease in objective criteria of the process acuity. It has been noted that duration of the remission was inversely proportional to the time of the inflammatory anamnesis. Provided the patients manifested exacerbation of the process, repeated courses of pulse therapy were conducted.
作者总结了对18例急性和亚急性非特异性主动脉动脉炎患者使用环磷酰胺和6-甲基泼尼松龙进行脉冲治疗所获得的初步经验。16例患者病情缓解,同时病情严重程度的客观标准有所降低。已经注意到,缓解期的持续时间与炎症病史的时间成反比。如果患者病情出现加重,则进行重复的脉冲治疗疗程。