[环磷酰胺长期胃肠外给药治疗系统性红斑狼疮合并中枢神经系统受累患者]
[The long-term parenteral use of cyclophosphane in treating patients with systemic lupus erythematosus and central nervous system involvement].
作者信息
Ivanova M M, Bliziuk O I, Travkina I V
出版信息
Ter Arkh. 1995;67(5):45-7.
PMID:7638778
Abstract
In the treatment of systemic lupus erythematosus (SLE) with acute CNS affections good results may be obtained with intravenous cyclophosphamide (CP) + methylprednisolone followed with long-term parenteral CP administration. CNS abnormalities in SLE patients can be effectively managed by parenteral CP in combination with minimal-dose glucocorticoids given for 5-7 years.
摘要
在治疗伴有急性中枢神经系统病变的系统性红斑狼疮（SLE）时，静脉注射环磷酰胺（CP）加甲基泼尼松龙，随后长期胃肠外给予CP，可能会取得良好效果。SLE患者的中枢神经系统异常可通过胃肠外给予CP联合小剂量糖皮质激素进行有效控制，持续用药5至7年。
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