Laboratory of Phytopathology, Wageningen University, Droevendaalsesteeg 1, 6708 PB Wageningen, The Netherlands.
Microbes Infect. 2011 Dec;13(14-15):1168-76. doi: 10.1016/j.micinf.2011.07.010. Epub 2011 Aug 5.
Despite the deployment of antifungal defence strategies, fungal diseases occur in all types of multicellular organisms. In plants, the role of fungal chitin as pathogen-associated molecular pattern that activates host defence is well established. Interestingly, plants employ homologs of the chitin immune receptors to initiate microbial symbiosis. Accumulating evidence shows that fungal pathogens developed secreted effectors to disarm chitin-triggered host immunity.
尽管已经采取了抗真菌防御策略，但真菌病仍会在所有类型的多细胞生物中发生。在植物中，真菌几丁质作为激活宿主防御的病原体相关分子模式的作用已得到充分证实。有趣的是，植物利用几丁质免疫受体的同源物来启动微生物共生。越来越多的证据表明，真菌病原体产生了分泌效应子来破坏几丁质触发的宿主免疫。
