Agarwal Anil, Qureshi Nadeem Akhtar, Khan Shariq Azam, Kumar Pawan, Samaiya Sachin
Department of Paediatric Orthopaedics, CNBC, Geeta Colony, Delhi, India.
J Orthop Surg (Hong Kong). 2011 Aug;19(2):213-7. doi: 10.1177/230949901101900217.
To report manifestations and management of tuberculosis of the foot and ankle in 21 children.
Records of 12 girls and 9 boys aged 3 to 14 (mean, 7) years with tuberculosis of the foot and ankle were reviewed. The mean delay in presentation was 4.7 (range, 0.5-14) months. All the patients had local swelling, tenderness, and antalgic gait; 16 were limping; 5 had an antecedent trauma; 11 had an abscess; and 6 had a discharging sinus. The diagnosis was based on a smear positive for acid-fast bacilli (n=2), histopathology (n=15), or clinicoradiological findings (n=4). Nine patients had osteoarticular tuberculosis in other parts of the body. None had evidence of pulmonary tuberculosis. Lesions were classified into synovial (articular) and osseous. All 3 synovial lesions occurred in the ankle, 2 of which were at an advanced stage. Osseous lesions occurred in the calcaneus (n=5), metatarsal (n=5), talus (n=3), cuboid (n=3), medial cuneiform (n=1), and phalanx (n=1), and were sub-classified into stages 1 (n=3), 2 (n=5), and 3 (n=10) according to disease progression. All the patients were treated conservatively with splintage and chemotherapy.
The mean follow-up period was 21 (range, 7-51) months. All the 3 patients with stage 1 osseous lesions showed healing within 6 weeks and had complete recovery of function. Four of the 5 patients with stage 2 lesions also showed complete recovery of function and reformation of bony trabeculations; radiological incorporation of sequestrum was obvious by 6 months in most patients. In patients with stage 3 lesions, healing was delayed and there was residual alteration in bony architecture and joint changes. Sclerotic changes and joint involvement also increased the likelihood of poor outcomes. However, none of our patients had any residual tenderness or foot deformity at the final follow-up.
Outcome after non-operative treatment is good, provided the lesions are treated early.
报告21例儿童足踝部结核的临床表现及治疗情况。
回顾12例女孩和9例男孩的病历,年龄3至14岁(平均7岁),均患有足踝部结核。就诊时平均延迟时间为4.7个月(范围0.5 - 14个月)。所有患者均有局部肿胀、压痛及痛性步态;16例跛行;5例有先前创伤史;11例有脓肿形成;6例有窦道流脓。诊断依据为抗酸杆菌涂片阳性(2例)、组织病理学检查(15例)或临床放射学表现(4例)。9例患者身体其他部位有骨关节结核。均无肺结核证据。病变分为滑膜(关节)型和骨型。3例滑膜型病变均发生于踝关节,其中2例处于晚期。骨型病变发生于跟骨(5例)、跖骨(5例)、距骨(3例)、骰骨(3例)、内侧楔骨(1例)和趾骨(1例),根据疾病进展分为1期(3例)、2期(5例)和3期(10例)。所有患者均采用夹板固定及化疗进行保守治疗。
平均随访期为21个月(范围7 - 51个月)。3例1期骨型病变患者在6周内均显示愈合,功能完全恢复。5例2期病变患者中有4例功能也完全恢复,骨小梁重新形成;多数患者在6个月时死骨的放射学融合明显。3期病变患者愈合延迟,骨结构有残留改变及关节变化。硬化改变及关节受累也增加了预后不良的可能性。然而,在末次随访时,我们的患者均无残留压痛或足部畸形。
只要病变早期得到治疗,非手术治疗的预后良好。