Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, 101 Section 2, Kuang-Fu Road, Hsinchu 30013, Taiwan.
Med Phys. 2011 Jul;38(7):4094-100. doi: 10.1118/1.3591989.
Polymethylmethacrylate (PMMA) slab is one of the mostly used phantoms for studying breast dosimetry in mammography. The purpose of this study was to evaluate the equivalence between exposure factors acquired from PMMA slabs and patient cases of different age groups of Taiwanese women in mammography.
This study included 3910 craniocaudal screen/film mammograms on Taiwanese women acquired on one mammographic unit. The tube loading, compressed breast thickness (CBT), compression force, tube voltage, and target/filter combination for each mammogram were collected for all patients. The glandularity and the equivalent thickness of PMMA were determined for each breast using the exposure factors of the breast in combination with experimental measurements from breast-tissue-equivalent attenuation slabs. Equivalent thicknesses of PMMA to the breasts of Taiwanese women were then estimated.
The average +/- standard deviation CBT and breast glandularity in this study were 4.2 +/- 1.0 cm and 54% +/- 23%, respectively. The average equivalent PMMA thickness was 4.0 +/- 0.7 cm. PMMA slabs producing equivalent exposure factors as in the breasts of Taiwanese women were determined for the age groups 30-49 yr and 50-69 yr. For the 4-cm PMMA slab, the CBT and glandularity values of the equivalent breast were 4.1 cm and 65%, respectively, for the age group 30-49 yr and 4.4 cm and 44%, respectively, for the age group 50-69 yr.
The average thickness of PMMA slabs producing the same exposure factors as observed in a large group of Taiwanese women is less than that reported for American women. The results from this study can provide useful information for determining a suitable thickness of PMMA for mammographic dose survey in Taiwan. The equivalence of PMMA slabs and the breasts of Taiwanese women is provided to allow average glandular dose assessment in clinical practice.
聚甲基丙烯酸甲酯(PMMA)板是用于研究乳房剂量学的最常用的体模之一。本研究的目的是评估在乳房 X 光摄影中,从 PMMA 板获得的曝光因子与不同年龄组台湾女性患者病例之间的等效性。
本研究纳入了在一台乳房 X 光摄影设备上获得的 3910 例台湾女性的头尾位屏/胶片乳房 X 光摄影。收集了每位患者的管加载量、压缩乳房厚度(CBT)、压缩力、管电压和靶/滤组合。使用乳房的曝光因子并结合乳腺组织等效衰减板的实验测量,确定了每个乳房的腺体含量和 PMMA 的等效厚度。然后估计了 PMMA 对台湾女性乳房的等效厚度。
本研究中平均(+/-标准偏差)CBT 和乳房腺体含量分别为 4.2(+/-1.0)cm 和 54%(+/-23%)。平均等效 PMMA 厚度为 4.0(+/-0.7)cm。确定了产生与台湾女性乳房等效曝光因子的 PMMA 板,用于 30-49 岁和 50-69 岁年龄组。对于 4cm PMMA 板,对于 30-49 岁年龄组,等效乳房的 CBT 和腺体含量值分别为 4.1cm 和 65%,对于 50-69 岁年龄组,分别为 4.4cm 和 44%。
产生与在一大组台湾女性中观察到的相同曝光因子的 PMMA 板的平均厚度小于报告的美国女性的厚度。本研究的结果可为确定台湾乳房 X 光摄影剂量调查中 PMMA 的合适厚度提供有用信息。提供 PMMA 板和台湾女性乳房的等效性,以允许在临床实践中评估平均腺体剂量。