Adhikary R, Joshi S
Department of Microbiology, Manipal Hospital, HAL Airport Road, Bangalore 560 017, India.
Indian J Med Microbiol. 2011 Jul-Sep;29(3):309-11. doi: 10.4103/0255-0857.83920.
Candidaemia is one of the leading causes of nosocomial bloodstream infections. There is a rise in the incidence of non-albicans candidaemia and emergence of anti-fungal resistance. We performed a retrospective laboratory-based study over a period of 2 years (January 2009 to December 2010) at our quaternary care multi super-specialty hospital in Southern India. There had been 68 Candida isolates detected from the bloodstream of 55 patients during the study period. Overall, 74% of cases were due to non-albicans Candida. C. tropicalis was most commonly isolated (39.7%), followed by C. albicans (26.4%). All Candida isolates remain susceptible to voriconazole, whereas highest degree of resistance was observed for fluconazole.
念珠菌血症是医院血流感染的主要原因之一。非白色念珠菌血症的发病率上升，且出现了抗真菌耐药性。我们在印度南部一家四级护理多专科综合医院进行了一项为期2年（2009年1月至2010年12月）的回顾性实验室研究。研究期间，从55名患者的血液中检测到68株念珠菌分离株。总体而言，74%的病例由非白色念珠菌引起。热带念珠菌最常被分离出来（39.7%），其次是白色念珠菌（26.4%）。所有念珠菌分离株对伏立康唑仍敏感，而氟康唑的耐药程度最高。
