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印度南部一家多专科超级中心念珠菌血症的菌种分布及抗真菌药敏情况

Species distribution and anti-fungal susceptibility of Candidaemia at a multi super-specialty center in Southern India.

作者信息

Adhikary R, Joshi S

机构信息

Department of Microbiology, Manipal Hospital, HAL Airport Road, Bangalore 560 017, India.

出版信息

Indian J Med Microbiol. 2011 Jul-Sep;29(3):309-11. doi: 10.4103/0255-0857.83920.

Abstract

Candidaemia is one of the leading causes of nosocomial bloodstream infections. There is a rise in the incidence of non-albicans candidaemia and emergence of anti-fungal resistance. We performed a retrospective laboratory-based study over a period of 2 years (January 2009 to December 2010) at our quaternary care multi super-specialty hospital in Southern India. There had been 68 Candida isolates detected from the bloodstream of 55 patients during the study period. Overall, 74% of cases were due to non-albicans Candida. C. tropicalis was most commonly isolated (39.7%), followed by C. albicans (26.4%). All Candida isolates remain susceptible to voriconazole, whereas highest degree of resistance was observed for fluconazole.

摘要

念珠菌血症是医院血流感染的主要原因之一。非白色念珠菌血症的发病率上升,且出现了抗真菌耐药性。我们在印度南部一家四级护理多专科综合医院进行了一项为期2年(2009年1月至2010年12月)的回顾性实验室研究。研究期间,从55名患者的血液中检测到68株念珠菌分离株。总体而言,74%的病例由非白色念珠菌引起。热带念珠菌最常被分离出来(39.7%),其次是白色念珠菌(26.4%)。所有念珠菌分离株对伏立康唑仍敏感,而氟康唑的耐药程度最高。

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