University of Patras, School of Medicine, Department of Microbiology, Patras, Greece.
Clin Microbiol Infect. 2010 Sep;16(9):1378-81. doi: 10.1111/j.1469-0691.2010.03193.x.
The aim of this study was to investigate the isolation and distribution rate of Candida spp. in blood cultures and evaluate antifungal susceptibility during an 11-year period (1998–2008) at a tertiary-care hospital. The causative species were as follows: Candida albicans, 163 strains (64%); Candida parapsilosis, 35 strains (13.7%); Candida glabrata, 25 strains (9.8%); Candida tropicalis, 19 strains (7.4%); and other Candida spp., 13 strains (5.1%). Candidaemia is predominantly caused by C. albicans. C. parapsilosis is the most common non-albicans Candida isolated in neonatal intensive-care units. All Candida isolates remain susceptible to amphotericin B, whereas the highest degree of resistance was observed for azoles.
本研究旨在调查 11 年间（1998-2008 年）在一家三级医院进行血培养中念珠菌属的分离和分布率，并评估抗真菌药敏情况。结果显示：白色念珠菌 163 株（64%），近平滑念珠菌 35 株（13.7%），光滑念珠菌 25 株（9.8%），热带念珠菌 19 株（7.4%），其他念珠菌属 13 株（5.1%）。念珠菌血症主要由白色念珠菌引起。在新生儿重症监护病房，最常见的非白色念珠菌是近平滑念珠菌。所有念珠菌分离株均对两性霉素 B 敏感，而唑类药物的耐药率最高。
