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阿巴卡利基儿童化脓性中耳炎:分离出的微生物及体外抗生素敏感性模式

Childhood suppurative otitis media in Abakaliki: isolated microbes and in vitro antibiotic sensitivity pattern.

作者信息

Nnebe-agumadu U, Okike O, Orji I, Ibekwe R C

机构信息

Department of Paediatrics, Ebonyi State University/Teaching Hospital, Abakaliki, Nigeria.

出版信息

Niger J Clin Pract. 2011 Apr-Jun;14(2):159-62. doi: 10.4103/1119-3077.84006.

Abstract

BACKGROUND

Suppurative otitis media (SOM) is the most common pediatric problem seen by otolaryngologists in Nigeria. Devising simple and effective ways of treating pediatric patients with suppurating ears, especially in situations without a specialist care, will help prevent chronicity. Our experience with som at the ebonyi state university teaching hospital (ebsuth), abakaliki, is reviewed in this study. it may serve as a guide in patient care.

OBJECTIVE

Determine the bacteriology of SOM in children in Abakaliki and ascertain their sensitivity to common antibiotics.

MATERIALS AND METHODS

A 2-year retrospective analysis of ear swabs culture results and case files of children aged 0-18 years with SOM managed in EBSUTH.

RESULTS

Sixty-five patients with discharging ears were reviewed. Of these, 73% were ≤ 5 years, of which 41.5% were infants. About 83% had unilateral ear discharge. Acute suppuration was seen in 67%. Overall swab yield was 87.7%; Pseudomonas was (57.4%), Klebsiella (16.4%), and Proteus species (11.5%). Ciprofloxacin showed 60% sensitivity, Gentamicin (58%), and Ceftazidime (35%). Amoxicillin/Clavulanic acid, ceftriaxone, and cefuroxime showed sensitivity of 4.3%-9.7%.

CONCLUSIONS

Treatment protocols of SOM in children should emphasize the use of Ciprofloxacin or Gentamicin, especially in situations with limited access to laboratory services or specialist care.

摘要

背景

化脓性中耳炎(SOM)是尼日利亚耳鼻喉科医生接诊的最常见儿科疾病。设计简单有效的方法来治疗耳朵化脓的儿科患者,尤其是在没有专科护理的情况下,将有助于预防病情慢性化。本研究回顾了我们在阿巴卡利基埃邦伊州立大学教学医院(EBSUTH)治疗SOM的经验。它可为患者护理提供指导。

目的

确定阿巴卡利基儿童SOM的细菌学情况,并确定其对常用抗生素的敏感性。

材料与方法

对在EBSUTH接受治疗的0至18岁SOM儿童的耳拭子培养结果和病例档案进行为期2年的回顾性分析。

结果

对65例耳部流脓患者进行了回顾。其中,73%的患者年龄≤5岁,其中41.5%为婴儿。约83%的患者单侧耳部流脓。67%的患者出现急性化脓。总体拭子阳性率为87.7%;铜绿假单胞菌(57.4%)、克雷伯菌(16.4%)和变形杆菌属(11.5%)。环丙沙星的敏感性为60%,庆大霉素(58%),头孢他啶(35%)。阿莫西林/克拉维酸、头孢曲松和头孢呋辛的敏感性为4.3%-9.7%。

结论

儿童SOM的治疗方案应强调使用环丙沙星或庆大霉素,尤其是在实验室服务或专科护理有限的情况下。

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