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慢性化脓性中耳炎患者的细菌谱及其药敏模式

Bacterial spectrum and their sensitivity pattern in patients of chronic suppurative otitis media.

作者信息

Sattar Abdul, Alamgir Ashar, Hussain Zakir, Sarfraz Salman, Nasir Jamal

机构信息

Department of Microbiology, Citi Lab, Rawalpindi, Pakistan.

出版信息

J Coll Physicians Surg Pak. 2012 Feb;22(2):128-9.

Abstract

The study was conducted from March 2008 to February 2010 in Microbiology Department, Citi Lab, Rawalpindi, to determine the causative microorganisms and their antibiotic sensitivity pattern in patients with chronic suppurative otitis media. One hundred and eighty-three samples received at Citi Lab were included in the study. Pus samples were cultured aerobically. Antibiotic sensitivity testing was done with standard antibiotic discs using modified Kirby-Bauer disk diffusion method. Out of 183 patients, microbiological culture was yielded from 154 specimens (84%). There were 148 bacterial isolates (96%) and 06 fungi (4%). Pseudomonas aeruginosa (n=59, 38%) was the most common isolate followed by Staphylococcus aureus (n=34, 22%). Susceptibility pattern of Pseudomonas aeruginosa showed that 100% isolates were sensitive to Piperacillin/Tazobactam, whereas 98% isolates were sensitive to Imipenem and 76% to Ciprofloxacin. Continuous surveillance of susceptibility pattern is suggestive for effective therapy of chronic suppurative otitis media.

摘要

该研究于2008年3月至2010年2月在拉瓦尔品第市立实验室微生物学部进行,以确定慢性化脓性中耳炎患者的致病微生物及其抗生素敏感性模式。市立实验室接收的183份样本被纳入研究。脓性样本进行需氧培养。使用改良的 Kirby-Bauer 纸片扩散法,用标准抗生素纸片进行抗生素敏感性测试。183例患者中,154份标本(84%)培养出微生物。有148株细菌分离株(96%)和6株真菌(4%)。铜绿假单胞菌(n = 59,38%)是最常见的分离株,其次是金黄色葡萄球菌(n = 34,22%)。铜绿假单胞菌的敏感性模式显示,100% 的分离株对哌拉西林/他唑巴坦敏感,而98% 的分离株对亚胺培南敏感,76% 对环丙沙星敏感。持续监测敏感性模式有助于慢性化脓性中耳炎的有效治疗。

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