Dor-Wojnarowska Anna, Rabski Marek, Fal Andrzej Mariusz, Liebhart Jerzy, Panaszek Bernard, Samoliński Bolesław
Klinika Chorób Wewnętrznych, Geriatrii i Alergologii Akademii Medycznej we Wrocławiu Kierownik: prof. dr hab. n. med. B. Panaszek.
Pneumonol Alergol Pol. 2011;79(5):320-5.
Measurement of peak nasal inspiratory flow (PNIF, peak nasal inspiratory flow) seems to be a cheap and simple method to assess nasal patency. Unfortunately, due to the lack of reference values a single measurement does not take any information about the degree of nasal obstruction. Therefore, the purpose of this study was to establish parameters useful for estimating PNIF reference values.
221 respondents, from Wrocław, answered a questionnaire based on ECRHS II and ISAAC. Sample was randomized based on the personal number, stratified and representative of age and sex. Subjects were divided into three groups on the basis of their age (6-7, 13-14 and 20-45 years). The PNIF was measured using an In-Check portable nasal inspiratory flow meter (In-Check's Clement-Clark). The highest of the five PNIF values was used as the measure of PNIF for each subject in subsequent analyses (PNIF MAX). Patients with rhinitis and/or asthma were withdrawn from the study.
Repeated measurements of PNIF were performed in 221 healthy volunteers. PNIF values were higher in males compared to women and this difference was statistically significant. There was a statistically significant correlation between height and PNIF MAX, and there was no such correlation between age and PNIF MAX. Stepwise linear regression that included gender, height, age revealed that only sex and height were independent significant predictors of PNIF. Obtained dependence PNIF MAX = -137.7 - 22.5 x + 1.7 y, where x is the sex (a woman, 0 - male) and the y - height. Coefficient of determination (R(2)) was 0.45 which means that regression equation explains about 45% of the observed PNIF MAX variability.
A correlation was found between PNIF value and sex and height of the patients, while age is irrelevant in this regard. Difficulty of establishing standards for the PNIF parameter are probably due to anatomical differences in the construction of the nose.
测量鼻吸气峰流量（PNIF）似乎是评估鼻腔通畅性的一种廉价且简单的方法。不幸的是，由于缺乏参考值，单次测量无法获取关于鼻阻塞程度的任何信息。因此，本研究的目的是建立有助于估计PNIF参考值的参数。
来自弗罗茨瓦夫的221名受访者回答了基于欧洲社区呼吸健康调查二期（ECRHS II）和国际儿童哮喘和过敏研究（ISAAC）的问卷。样本根据个人编号进行随机分组，按年龄和性别分层且具有代表性。受试者根据年龄分为三组（6 - 7岁、13 - 14岁和20 - 45岁）。使用In-Check便携式鼻吸气流量计（In-Check的克莱门特-克拉克公司生产）测量PNIF。在后续分析中，将每个受试者五次PNIF值中的最高值用作PNIF的测量值（PNIF MAX）。患有鼻炎和/或哮喘的患者被排除在研究之外。
对221名健康志愿者进行了PNIF的重复测量。男性的PNIF值高于女性，且这种差异具有统计学意义。身高与PNIF MAX之间存在统计学上的显著相关性，而年龄与PNIF MAX之间不存在这种相关性。纳入性别、身高、年龄的逐步线性回归显示，只有性别和身高是PNIF的独立显著预测因素。得到的关系式为PNIF MAX = -137.7 - 22.5x + 1.7y，其中x为性别（女性为0，男性为1），y为身高。决定系数（R²）为0.45，这意味着回归方程解释了约45%的观察到的PNIF MAX变异性。
发现PNIF值与患者的性别和身高之间存在相关性，而年龄在这方面无关紧要。PNIF参数难以建立标准可能是由于鼻子结构的解剖学差异。
