在峰值鼻吸气流量测量中消除鼻瓣阻塞。

Removing nasal valve obstruction in peak nasal inspiratory flow measurement.

作者信息

Barnes Martyn L, Lipworth Brian J

机构信息

Asthma and Allergy Research Group, Department of Medicine and Therapeutics, Ninewells Hospital and Perth Royal Infirmary, University of Dundee, Dundee, Scotland.

出版信息

Ann Allergy Asthma Immunol. 2007 Jul;99(1):59-60. doi: 10.1016/S1081-1206(10)60622-9.

DOI:10.1016/S1081-1206(10)60622-9

PMID:17650831

Abstract

BACKGROUND

Peak nasal inspiratory flow (PNIF) measurements are used to evaluate nasal obstruction and as a surrogate for disease activity in allergic rhinitis and other nasal complaints. This measurement can give erroneous results when forced inspiration leads to nasal valve collapse.

OBJECTIVE

To determine the effects of 2 different nasal stents (Sinuscone and Nozovent) on valve collapse and repeatability of PNIF measurements.

METHODS

Repeated measurements of PNIF were obtained in 74 individuals with and without 2 different nasal stents: Sinuscone and Nozovent.

RESULTS

The mean (95% confidence interval) improvement in PNIF was 1.7 L/min (-2.4 to 5.8 L/min; P = .42) with Nozovents and 25.4 L/min (11.4 to 39.4 L/min; P = .001) with Sinuscones. The PNIF coefficient of variation for repeatability was 11.6% without stents, 16.0% using Nozovents, and 10.4% using Sinuscones.

CONCLUSIONS

Sinuscones, but not Nozovents, significantly improved PNIF. Repeatability of PNIF measurements was worse with Nozovents and only marginally improved with Sinuscones.

摘要

背景

鼻吸气峰流量（PNIF）测量用于评估鼻阻塞情况，并作为变应性鼻炎和其他鼻部疾病活动的替代指标。当用力吸气导致鼻瓣塌陷时，该测量可能会得出错误结果。

目的

确定两种不同鼻支架（Sinuscone和Nozovent）对鼻瓣塌陷及PNIF测量重复性的影响。

方法

对74名佩戴和未佩戴两种不同鼻支架（Sinuscone和Nozovent）的个体进行PNIF重复测量。

结果

使用Nozovent时，PNIF的平均改善值（95%置信区间）为1.7升/分钟（-2.4至5.8升/分钟；P = 0.42），使用Sinuscone时为25.4升/分钟（11.4至39.4升/分钟；P = 0.001）。无支架时PNIF重复性的变异系数为11.6%，使用Nozovent时为16.0%，使用Sinuscone时为10.4%。