Krzych-Fałta Edyta, Lusawa Adam, Samoliński Bolesław
Zakład Profilaktyki Zagrozeń Srodowiskowych i Alergologii, Warszawski Uniwersytet Medyczny.
Przegl Lek. 2012;69(10):764-8.
The aim of the study was to evaluate the usefulness of PNIF in assessing nasal airway patency based on test results. The sample in the study was a group of 4 674 subjects, including 1291 people aged 6-7 years (woman 643, men 648), 1293 people aged 13-14 years (woman 625, men 668) and 2090 adults (woman 1284, men 806). The research method employed in the study was the measurement of peak nasal inspiratory flow using a peak flow meter with a suitable mask as used in rhinomanometry tests and with a flow rate ranging from 20 to 350 l/min. The study was conducted in 2006-2008 at the following centres: Katowice, Wroclaw, Krakow, Lublin, Warszawa, Bydgoszcz, Gdansk and in the rural areas of the former province of Zamosc.
For the purposes of the study, the average values for the subjects were calculated for a number of criteria: - subject age: The average PNIF value was 52,41/min for subjects aged 6-7 years(n=1291), 94.7 l/min for subjects aged 13-14 (n=1293) and 108.0 l/min for the adults (n=2090). Indeed statistical dependences for all aged groups were observed on level p<0,0005. -diagnosis: The average PNIF value for healthy was 52,3 l/min p=0,338 for subjects aged 6-7 years (n=680), 97,3 l/min p=0,279 for subjects aged 13-14 (n=640) and 111,7 l/min p=0,438 for the adults (n=1035) and for allergic rhinitis PNIF value was 50,41/min p=0,028 for subjects aged 6-7 years(n=310), 93,3 l/min p=0,299 for subjects aged 13-14 (n=389) and 107,71 1/min p=0,276 for the adults (n=623) and asthma PNIF value was 51,6/min for subjects aged 6-7 years(n=149) 87,3 l/min p=0,062 for subjects aged 13-14 (n=145) p=0,097 and 105,3 l/min p=0,13 for the adults (n=198) -exposure to tobacco smoke (adults): passive smoking - 105,311 min (n=1202) p=0,017, active smoking-119.1 l/min(n=885) p=0,108.
PINF is important investigative tool thanks which we can: to differentiate in dependence the functional state of nose from: put the recognition (the patients with allergic rhinitis, the bronchial asthma), the age and the studied sexes.
本研究旨在根据测试结果评估鼻吸气峰流量(PNIF)在评估鼻气道通畅性方面的实用性。研究样本为4674名受试者,包括1291名6至7岁的儿童(女性643名,男性648名)、1293名13至14岁的青少年(女性625名,男性668名)和2090名成年人(女性1284名,男性806名)。本研究采用的研究方法是使用峰值流量计测量鼻吸气峰流量,该峰值流量计配有在鼻阻力测试中使用的合适面罩,流速范围为20至350升/分钟。该研究于2006年至2008年在以下中心进行:卡托维兹、弗罗茨瓦夫、克拉科夫、卢布林、华沙、比得哥什、格但斯克以及前扎莫希奇省的农村地区。
为了本研究的目的,针对若干标准计算了受试者的平均值:- 受试者年龄:6至7岁受试者的平均PNIF值为52.4升/分钟(n = 1291),13至14岁受试者为94.7升/分钟(n = 1293),成人为108.0升/分钟(n = 2090)。实际上,在所有年龄组中均观察到p<0.0005水平的统计学相关性。- 诊断:6至7岁健康受试者的平均PNIF值为52.3升/分钟(p = 0.338,n = 680),13至14岁受试者为97.3升/分钟(p = 0.279,n = 640),成人为111.7升/分钟(p = 0.438,n = 1035);变应性鼻炎患者6至7岁受试者的PNIF值为50.4升/分钟(p = 0.028,n = 310),13至14岁受试者为93.3升/分钟(p = 0.299,n = 389),成人为107.7升/分钟(p = 0.276,n = 623);哮喘患者6至7岁受试者的PNIF值为51.6升/分钟(n = 149),13至14岁受试者为87.3升/分钟(p = 0.062,n = 145),成人为105.3升/分钟(p = 0.097,n = 198)。- 接触烟草烟雾(成年人):被动吸烟 - 105.3升/分钟(n = 1202,p = 0.017),主动吸烟 - 119.1升/分钟(n = 885,p = 0.108)。
PNIF是一种重要的研究工具,通过它我们可以:根据年龄、所研究的性别以及是否患有变应性鼻炎、支气管哮喘等疾病来区分鼻子的功能状态。