Department of Pharmaceutical Sciences, Nutritional and Health Sciences, University of Calabria, Italy.
Nat Prod Res. 2012;26(1):91-7. doi: 10.1080/14786419.2010.545356. Epub 2011 Aug 23.
The two studied Calamintha species showed different polyphenolic content and sterol composition. Calamintha grandiflora possessed twice the polyphenolic content of Calamintha nepeta subsp. glandulosa, while the latter contained a higher number of sterols. Among them, stigmast-5-en-3β-ol was found to be the major constituent. The methanolic extract of C. grandiflora was more potent than the C. nepeta subsp. glandulosa methanolic extract in a DPPH assay, while the activity of the C. grandiflora EtOAc fraction was weaker than its C. nepeta subsp. glandulosa counterpart. Fractions of C. nepeta subsp. glandulosa showed higher activity using a β-carotene bleaching test. The petrol ether fraction of C. grandiflora showed significant inhibition of NO production.
这两种荆芥属植物表现出不同的多酚含量和甾醇组成。大花香水芥的多酚含量是腺花香水芥的两倍，而后者含有更多数量的甾醇。其中，发现豆甾-5-烯-3β-醇是主要成分。在 DPPH 测定中，大花香水芥的甲醇提取物比腺花香水芥的甲醇提取物更有效，而大花香水芥的 EtOAc 部分的活性则弱于腺花香水芥。用β-胡萝卜素漂白试验，腺花香水芥的各个部分显示出更高的活性。大花香水芥的石油醚部分显示出对 NO 产生的显著抑制作用。
