Department of Biochemistry and Biotechnology, University of Thessaly, Ploutonos 26 and Aiolou, Larissa 41221, Greece.
Food Chem Toxicol. 2012 Nov;50(11):4115-24. doi: 10.1016/j.fct.2012.08.033. Epub 2012 Aug 24.
Lamiaceae family species are considered important because of their use in folk medicine, culinary and flavouring throughout the world. Their interesting bioactivities are attributed mainly to essential oils, polyphenols and terpenes. However, there are only few studies about polyphenolic extracts from Lamiaceae plants. Thus, 24 polyphenolic extracts from three Lamiaceae genera, Salvia, Mentha and Sideritis, collected in Greece were examined for antioxidant and antibacterial activity in correlation with their polyphenolic content. The results showed that the tested polyphenolic extracts had strong free radical scavenging activity against DPPH· and ABTS(+) radicals and protected from hydroxyl and peroxyl radical-induced DNA damage. Moreover, five extracts inhibited Staphylococcus aureus growth. Furthermore, the results showed that the total polyphenolic content is not correlated with the above activities, although this relation was different within each plant genus. This is the first study regarding the antioxidant and antibacterial activity of Salvia pomifera ssp. calycina, S. pomifera ssp. pomifera, Mentha microphylla and Sideritis raeseri ssp. attica species, and one of the few concerning protection from DNA damage and antibacterial activity of polyphenolic extracts from the rest of the tested species.
唇形科物种因其在民间医学、烹饪和调味方面的用途而被认为很重要。它们的有趣生物活性主要归因于精油、多酚和萜烯。然而，关于唇形科植物的多酚提取物的研究很少。因此，研究了希腊采集的三个唇形科属（鼠尾草属、薄荷属和山小橘属）的 24 种多酚提取物，以研究其与多酚含量相关的抗氧化和抗菌活性。结果表明，测试的多酚提取物对 DPPH·和 ABTS(+)自由基具有很强的清除自由基活性，并能防止羟基和过氧自由基诱导的 DNA 损伤。此外，有 5 种提取物抑制了金黄色葡萄球菌的生长。此外，结果表明，总多酚含量与上述活性没有相关性，尽管在每个植物属内这种关系是不同的。这是首次研究萨福刺蕊草、萨福刺蕊草、细叶薄荷和山小橘属的山小橘种的抗氧化和抗菌活性，也是少数几个关于其余测试物种的多酚提取物对 DNA 损伤保护和抗菌活性的研究之一。
