Caramia M, Taddei G, Nobilini A
Divisione Pediatrica, Ospedale dei Bambini, G. Salesi, Ancona.
Minerva Pediatr. 1990 Jan-Feb;42(1-2):29-34.
The continual use of antibiotics and the defence works of microorganisms have induced less activity of many antibiotics once particularly effective for their excellent therapeutic index. The association of clavulanic acid with amoxicillin, the latter a long time used for its excellent therapeutic index particularly in respiratory tract infections, has restored and some ways potentiated the once activity of the latter.
抗生素的持续使用以及微生物的防御机制,使得许多曾经因其出色治疗指数而特别有效的抗生素活性降低。克拉维酸与阿莫西林联合使用,阿莫西林长期以来因其出色的治疗指数,尤其在呼吸道感染方面而被广泛使用,这恢复了阿莫西林的活性,并在某些方面增强了其活性。