Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Circ Heart Fail. 2011 Sep;4(5):589-98. doi: 10.1161/CIRCHEARTFAILURE.110.960484. Epub 2011 Aug 23.
Although women account for a significant proportion of heart failure (HF) hospitalizations, data on the quality of care and in-hospital outcomes in women are limited.
We examined The Joint Commission performance measures, other quality metrics, length of stay, and in-hospital mortality in women using 99 841 HF admissions (January 2005 to June 2009) at 248 hospitals participating in the American Heart Association Get With The Guidelines-Heart Failure registry. Women accounted for 50% of the HF admissions and were older (mean age, 74±14 versus 69±14 years), more likely to have hypertension (77% versus 72%), and less likely to have coronary disease (44% versus 53%) or renal insufficiency (18% versus 23%) than men (all P<0.001). The presenting symptoms were similar to men, but women had higher admission systolic blood pressure (mean, 144±31 versus 137±30 mm Hg; P<0.001) and ejection fraction (mean, 0.44±0.17% versus 0.34±0.16%; P<0.001). After adjustment for baseline differences, eligible women were less likely than men to have measurement of left ventricular function (adjusted odds ratio [OR], 0.81; 95% CI, 0.76 to 0.86) and to receive anticoagulation for atrial fibrillation (adjusted OR, 0.91; 95% CI, 0.86 to 0.96) or implantable cardioverter-defibrillators (adjusted OR, 0.70; 95% CI, 0.65 to 0.75) but were as likely to receive discharge instructions, angiotensin-converting enzyme inhibitors/angiotensin receptor blockers, β-blockers, and smoking cessation counseling at discharge. Although the median length of stay was 4 days, women were more likely than men to be hospitalized >4 days (adjusted OR, 1.13; 95% CI, 1.10 to 1.16) and >7 days (adjusted OR, 1.07; 95% CI, 1.04 to 1.11). Women had comparable in-hospital mortality to men (adjusted OR, 1.05; 95% CI, 0.96 to 1.14).
Compared to men, women hospitalized for HF differ in many clinical characteristics and length of stay but have similar clinical presentations, receive similar quality of care for most but not all measures, and experience similar in-hospital mortality.
尽管女性在心力衰竭(HF)住院患者中占有相当大的比例,但有关女性护理质量和住院结局的数据有限。
我们使用参加美国心脏协会“达标-心力衰竭”注册研究的 248 家医院 2005 年 1 月至 2009 年 6 月期间的 99841 例 HF 住院患者(99841 例),评估了联合委员会的绩效指标、其他质量指标、住院时间和院内死亡率。女性占 HF 住院患者的 50%,年龄更大(平均年龄 74±14 岁 vs. 69±14 岁),更可能患有高血压(77% vs. 72%),而更可能患有冠心病(44% vs. 53%)或肾功能不全(18% vs. 23%)比男性(均 P<0.001)。其临床表现与男性相似,但女性的入院收缩压(平均 144±31 比 137±30mmHg;P<0.001)和射血分数(平均 0.44±0.17%比 0.34±0.16%;P<0.001)更高。调整基线差异后,与男性相比,合格女性接受左心室功能检测的可能性更小(校正比值比 [OR],0.81;95%可信区间,0.76 至 0.86),接受心房颤动抗凝治疗(校正 OR,0.91;95%可信区间,0.86 至 0.96)或植入式心脏复律除颤器(校正 OR,0.70;95%可信区间,0.65 至 0.75)的可能性更小,但接受出院指导、血管紧张素转换酶抑制剂/血管紧张素受体阻滞剂、β受体阻滞剂和戒烟咨询的可能性与男性相同。尽管中位住院时间为 4 天,但女性住院时间超过 4 天(校正 OR,1.13;95%可信区间,1.10 至 1.16)和超过 7 天(校正 OR,1.07;95%可信区间,1.04 至 1.11)的可能性大于男性。女性院内死亡率与男性相似(校正 OR,1.05;95%可信区间,0.96 至 1.14)。
与男性相比,因 HF 住院的女性在许多临床特征和住院时间方面存在差异,但临床表现相似,接受大多数但不是所有措施的护理质量相似,且院内死亡率相似。