3T 下钆增强脂肪饱和 T1 加权 FLAIR 与快速自旋回波 MRI 对脊柱硬膜外病变的评估比较。

Comparison of gadolinium-enhanced fat-saturated T1-weighted FLAIR and fast spin-echo MRI of the spine at 3 T for evaluation of extradural lesions.

机构信息

Department of Diagnostic Imaging, University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Unit 370, Houston, TX 77030, USA.

出版信息

AJR Am J Roentgenol. 2011 Sep;197(3):697-703. doi: 10.2214/AJR.10.4887.

DOI:10.2214/AJR.10.4887

PMID:21862814

Abstract

OBJECTIVE

Inversion recovery has been used to correct the loss of CSF and tissue contrast at 3 T versus 1.5 T but has not been formally investigated in the spine after IV administration of gadolinium-based contrast agent. The purpose of this study is to compare two sequences for gadolinium-enhanced spine imaging at 3 T--fat-saturated T1-weighted FLAIR and fat-saturated T1-weighted fast spin-echo (FSE)--for evaluation of extradural lesions and CSF-cord contrast.

MATERIALS AND METHODS

After IV administration of gadolinium-based contrast agent, fat-saturated T1-weighted FSE and FLAIR sequences were obtained in 156 MRI scans of 143 patients at 3 T. Three experienced radiologists compared these sequences for conspicuity differences in bone lesions, disk lesions, other epidural lesions, and cord-CSF contrast. A 7-point visual rating scale was used, with lower numbers indicating increased conspicuity on gadolinium-enhanced fat-saturated T1-weighted FLAIR and higher numbers indicating increased conspicuity on gadolinium-enhanced fat-saturated T1-weighted FSE.

RESULTS

A slight increase in the conspicuity of gadolinium-enhancing bone lesions (mean score, 3.6; p < 0.0001), disk lesions (mean score, 3.5; p < 0.0001), and epidural lesions (mean score, 3.4; p < 0.0001) was seen on fat-saturated T1-weighted FLAIR compared with fat-saturated T1-weighted FSE. A higher degree of contrast between the spinal cord and CSF was seen on fat-saturated T1-weighted FLAIR, by a large margin (mean score, 1.8; p < 0.0001). All enhancing lesions seen on fat-saturated T1-weighted FSE images were also seen on fat-saturated T1-weighted FLAIR images.

CONCLUSION

Decreased CSF-cord contrast at 3 T, as seen on T1-weighted FSE, can be regained by using T1-weighted FLAIR. Fat-saturated T1-weighted FLAIR may increase conspicuity of gadolinium-enhancing extradural lesions compared with fat-saturated T1-weighted FSE.

摘要

目的

反转恢复已被用于校正在 3T 与 1.5T 时 CSF 和组织对比的损失，但尚未在静脉注射钆基造影剂后正式研究脊柱。本研究的目的是比较两种序列在 3T 下增强的脊柱成像-脂肪饱和 T1 加权 FLAIR 和脂肪饱和 T1 加权快速自旋回波（FSE）-用于评估硬膜外病变和 CSF-脊髓对比。

材料和方法

在 143 例患者的 156 例 MRI 扫描中，在 3T 时静脉注射钆基造影剂后，获得了脂肪饱和 T1 加权 FSE 和 FLAIR 序列。三位经验丰富的放射科医生比较了这些序列在骨病变、椎间盘病变、其他硬膜外病变和脊髓-CSF 对比方面的显影差异。使用 7 分视觉评分量表，较低的数字表示增强的脂肪饱和 T1 加权 FLAIR 上的显影增加，较高的数字表示增强的脂肪饱和 T1 加权 FSE 上的显影增加。

结果

与脂肪饱和 T1 加权 FSE 相比，在脂肪饱和 T1 加权 FLAIR 上观察到增强的骨病变（平均评分 3.6；p <0.0001）、椎间盘病变（平均评分 3.5；p <0.0001）和硬膜外病变（平均评分 3.4；p <0.0001）的显影略有增加。在脂肪饱和 T1 加权 FLAIR 上，脊髓和 CSF 之间的对比度更高，差异很大（平均评分 1.8；p <0.0001）。在脂肪饱和 T1 加权 FSE 图像上看到的所有增强病变也在脂肪饱和 T1 加权 FLAIR 图像上看到。