Bone marrow transplant. Recent advances and nursing implications.

The myriad therapies used during bone marrow transplantation are in constant flux. Major problems still need to be solved including relapse after transplant and graft rejection. More effective and less toxic conditioning regimens, acceleration of hematopoietic and immune reconstruction, and improved control of GVHD and infections are currently being studied. Nurses are vital in orchestrating the complicated care these therapies mandate as well as providing emotional support to patients and their families. Nursing research is being conducted in many areas of marrow transplantation. Quality-of-life and survivor issues have been identified as priorities by many nurses working in this field. Nurses will continue to play a pivotal role in caring for patients as marrow transplantation continues to evolve as a major form of cancer treatment.