弓形体病性视网膜炎后抗磷脂综合征。
Antiphospholipid syndrome following toxoplasma retinochoroiditis.
机构信息
Ophthalmology Department and Ophthalmic Research Center, Labbafinejad Medical Center, Shahid Beheshti Medical University, Tehran, Iran.
出版信息
Ocul Immunol Inflamm. 2011 Oct;19(5):311-3. doi: 10.3109/09273948.2011.596302. Epub 2011 Aug 24.
PURPOSE
To report a case of antiphospholipid syndrome (APS) following toxoplasma retinochoroiditis.
DESIGN
Interventional case report.
METHOD
The patient was a 24-year-old female with an attack of visual loss due to toxoplasma retinochoroiditis concomitant with branch retinal vein occlusion. Retinitis resolved with anti-toxoplasma treatment. However, a recurrent episode of BRVO and vitreous hemorrhage occurred later.
RESULT
In systemic evaluation, evidence of APS was detected, including high titers of anti-cardiolipin antibody, increased beta-2 microglobulin and anti-toxoplasma IgG antibody, and also low titers of C3, C4, and CH50.
CONCLUSION
Ocular toxoplasmosis should be included in the list of etiologies of secondary APS. Systemic evaluation for detection of APS is a necessary approach to patients with toxoplasma retinochoroiditis and concomitant vascular accident.
目的
报告 1 例弓形体病性视网膜炎继发抗磷脂综合征（APS）。
设计
介入性病例报告。
方法
患者为 24 岁女性，因弓形体病性视网膜炎伴分支视网膜静脉阻塞而出现视力丧失。经抗弓形体治疗后视网膜炎消退，但后来又发生了 BRVO 和玻璃体积血的复发性发作。
结果
在系统评估中，发现了 APS 的证据，包括抗心磷脂抗体滴度高、β-2 微球蛋白和抗弓形体 IgG 抗体增加，以及 C3、C4 和 CH50 滴度降低。
结论
眼弓形体病应列入继发性 APS 的病因之一。对伴有血管意外的弓形体病性视网膜炎患者进行 APS 的系统评估是必要的。
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