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[动脉高血压的血流动力学]

[Hemodynamics of arterial hypertension].

作者信息

Navarro Salas E, Placer Peralta L J

机构信息

Servicio de Cardiología, Hospital Miguel Servet, Zaragoza.

出版信息

Rev Esp Cardiol. 1990;43 Suppl 1:34-6.

PMID:2186452
Abstract

Arterial blood pressure depends on the flow rate and peripheral resistances. Arterial blood pressure is regulated in arterial hypertension (AHT) in a very similar fashion as in normotensive subjects, but the peripheral vessels do not respond properly to increases in the cardiac output. The adrenergic nervous system plays a basic part in the mechanisms which provoke and regulate the AHT. The AHT usually begins with an increase in adrenergic tone and cardiac output: hyperkinetic hypertension. It later develops into an intermediate, normokinetic situation with latent left ventricular malfunction and finally augmented peripheral resistances which will become of organic character in time due to autoregulatory mechanisms.

摘要

动脉血压取决于血流量和外周阻力。动脉高血压(AHT)时动脉血压的调节方式与血压正常者非常相似,但外周血管对心输出量增加的反应不正常。肾上腺素能神经系统在引发和调节AHT的机制中起基本作用。AHT通常始于肾上腺素能张力和心输出量增加:即高动力性高血压。随后发展为中间的、正常动力状态,伴有潜在的左心室功能障碍,最终外周阻力增加,由于自身调节机制,这种外周阻力增加最终将具有器质性特征。

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