Ljubicić N, Duvnjak M, Rotkvić I, Kopjar B
Dept. of Gastroenterology and Hepatology, Ultrasonic Institute University, Zagreb, Dr Josip Kajfes General Hospital, Yugoslavia.
Scand J Gastroenterol. 1990 Apr;25(4):395-400. doi: 10.3109/00365529009095505.
Portal vein haemodynamics as demonstrated by the pulsed Doppler system were studied in 37 patients with cirrhosis who had been classified in three groups (A, B, and C) in accordance with the degree of liver failure. Maximal inner diameter of the portal vein was significantly lower in patients who were considered to be in good condition (group A) than in patients with moderate and severe liver failure (group B and group C) (p less than 0.001). A significant difference was also found between group A and group B and between group A and group C with regard to the portal blood velocity and portal blood flow (p less than 0.001). In accordance with the presence and size of the oesophageal varices, in patients with large varices the portal blood velocity and portal blood flow were significantly lower than in patients without varices (p less than 0.001), whereas maximal inner portal vein diameter was significantly higher (p less than 0.001). This study demonstrated that in patients with cirrhosis circulatory alterations in the portal vascular bed may be, at least in part, an indicator of the stage of liver disease.
采用脉冲多普勒系统对37例肝硬化患者的门静脉血流动力学进行了研究，这些患者已根据肝功能衰竭程度分为三组（A组、B组和C组）。被认为状况良好的患者（A组）门静脉最大内径显著低于中度和重度肝功能衰竭患者（B组和C组）（p<0.001）。在门静脉血流速度和门静脉血流量方面，A组与B组以及A组与C组之间也存在显著差异（p<0.001）。根据食管静脉曲张的有无及大小，有大静脉曲张的患者门静脉血流速度和门静脉血流量显著低于无静脉曲张的患者（p<0.001），而门静脉最大内径显著更高（p<0.001）。本研究表明，肝硬化患者门静脉血管床的循环改变可能至少部分是肝病分期的一个指标。
