Ogholoh Oghenetejiri Denise, Zaccheus Akintunde Oluwaseunayo, Ikubor Joyce Ekeme, Nwafor Nkem Nnenna, Idowu Bukunmi Michael, Ogholoh Gregory Iremhien
Department of Radiology, Delta State University, Abraka and Delta State University Teaching Hospital, Oghara, Delta State, Nigeria.
Department of Radiology, Lagoon Hospitals, Ikeja, Lagos State, Nigeria.
J Ultrason. 2023 May 11;23(93):e53-e60. doi: 10.15557/jou.2023.0011. eCollection 2023 Jun.
Portal vein congestion index has shown promise in detecting early portal venous hemodynamic changes in chronic liver disease. The aim of this study was to compare the portal vein congestion index of adult patients with chronic liver disease to that of healthy controls, and to evaluate the differences in portal vein congestion index, if any, between the common etiologies of chronic liver disease (chronic viral hepatitis, alcoholic liver disease, and non-alcoholic fatty liver disease).
Eighty participants with chronic liver disease and 80 healthy controls had their sociodemographic variables, anthropometric indices, liver size/echotexture, spleen size, presence of ascites, and portal vein parameters (diameter, cross-sectional area, velocity, and congestion index) evaluated. ≤0.05 was considered statistically significant.
There were 48 (60%) males and 32 (40%) females in the control group, while 56 (70%) males and 24 (30%) females were included in the chronic liver disease group ( = 0.185). Of the eighty people with chronic liver disease, 57 (71.2%) were diagnosed with alcoholic liver disease, while 23 (28.8%) were diagnosed with chronic viral hepatitis. There were no cases of non-alcoholic fatty liver disease during the study period. The mean liver spans of the control and chronic liver disease groups were 13.45 ± 0.85 cm and 16.50 ± 4.96 cm, respectively. All the controls had normal hepatic parenchymal echogenicity, while 45 (56.3%) subjects with chronic liver disease (36 alcoholic liver disease and 9 chronic viral hepatitis) had increased hepatic echogenicity. The mean values of the portal vein congestion index for the control and chronic liver disease groups were 0.0775 ± 0.02 cm/sec and 0.1037 ± 0.03 cm/sec, respectively ( <0.0001).
The chronic liver disease group showed a significantly higher mean portal vein congestion index than the control group.
门静脉充血指数在检测慢性肝病早期门静脉血流动力学变化方面显示出前景。本研究的目的是比较成年慢性肝病患者与健康对照者的门静脉充血指数，并评估慢性肝病常见病因（慢性病毒性肝炎、酒精性肝病和非酒精性脂肪性肝病）之间门静脉充血指数的差异（如有）。
对80名慢性肝病患者和80名健康对照者的社会人口统计学变量、人体测量指标、肝脏大小/回声质地、脾脏大小、腹水情况以及门静脉参数（直径、横截面积、流速和充血指数）进行评估。P≤0.05被认为具有统计学意义。
对照组有48名（60%）男性和32名（40%）女性，而慢性肝病组有56名（70%）男性和24名（30%）女性（P = 0.185）。在80名慢性肝病患者中，57名（71.2%）被诊断为酒精性肝病，而23名（28.8%）被诊断为慢性病毒性肝炎。研究期间无非酒精性脂肪性肝病病例。对照组和慢性肝病组的平均肝左右径分别为13.45±0.85厘米和16.50±4.96厘米。所有对照者肝实质回声正常，而45名（56.3%）慢性肝病患者（36名酒精性肝病患者和9名慢性病毒性肝炎患者）肝回声增强。对照组和慢性肝病组的门静脉充血指数平均值分别为0.0775±0.02厘米/秒和0.1037±0.03厘米/秒（P<0.0001）。
慢性肝病组的平均门静脉充血指数显著高于对照组。
