Aoike Ikuo
Koyo Medical Clinic, Kameda-Koyo, Konan-Ku, Niigata, Japan.
Contrib Nephrol. 2011;173:53-57. doi: 10.1159/000328953. Epub 2011 Aug 8.
The clinical benefits of high-performance membrane (HPM) dialyzers have often been reported since the advent of the synthetic polyacrylonitrile dialysis membrane. HPMs, which have high water permeability, eliminate a wide spectrum of uremic toxins, and offer excellent biocompatibility, are now essential for hemodialysis, hemofiltration, and hemodiafiltration. For HPMs whose mean pore size is enlarged to secure better dialysis membrane performance, however, the dialyzing fluid must be highly purified to prevent contamination. Blood purification therapies using highly purified dialyzing fluid and HPM are expected to improve the prognosis of future patients undergoing dialysis.
自从合成聚丙烯腈透析膜问世以来，高性能膜（HPM）透析器的临床益处经常被报道。HPM具有高水渗透性，能清除多种尿毒症毒素，并具有出色的生物相容性，如今对于血液透析、血液滤过和血液透析滤过至关重要。然而，对于那些平均孔径增大以确保更好透析膜性能的HPM，透析液必须高度纯化以防止污染。使用高度纯化透析液和HPM的血液净化疗法有望改善未来接受透析患者的预后。
