Weber Rebecca J, Taylor Brent R, Engelman Dendy E
Curr Probl Dermatol. 2011;42:24-34. doi: 10.1159/000328241. Epub 2011 Aug 16.
Knowledge of laser tissue reactions and tissue properties allows the practitioner to tailor a treatment to an individual patient's need and goals. A laser's power, spot size and pulse duration may be manipulated to yield different tissue reactions. Five tissue reactions, each the result of varying laser pulse durations and energy densities, may be achieved. They are photochemical, photothermal, photoablation, plasma-induced ablation and photomechanical. Of these, photothermal reactions are most utilized in dermatology. When higher powered pulses are applied, tissue often undergoes multiple reactions simultaneously. An understanding of these reactions allows their effects to be predicted. In this chapter, the various reactions are reviewed, and the reactions caused by many of the most commonly used lasers in dermatology are discussed.
了解激光与组织的相互作用以及组织特性,有助于从业者根据个体患者的需求和目标制定个性化治疗方案。可以通过控制激光的功率、光斑大小和脉冲持续时间来产生不同的组织反应。通过改变激光脉冲持续时间和能量密度,可实现五种组织反应。它们分别是光化学、光热、光消融、等离子体诱导消融和光机械反应。其中,光热反应在皮肤科应用最为广泛。当使用高功率脉冲时,组织通常会同时发生多种反应。了解这些反应有助于预测其效果。在本章中,将对各种反应进行综述,并讨论皮肤科许多常用激光所引起的反应。