Valentine S, McVey F K, Coe A
Department of Anaesthetics, Bristol Royal Infirmary.
Anaesthesia. 1990 Apr;45(4):306-8. doi: 10.1111/j.1365-2044.1990.tb14738.x.
A randomised double-blind trial was conducted to study the use of two commonly used premedication regimens and the subsequent incidence of sore throat. Fifty adult patients who underwent routine surgery were anaesthetised in a standard fashion after premedication with papaveretum and scopolamine or temazepam, and interviewed after operation to assess the presence of sore throat. A significantly higher incidence of sore throat was associated with the use of papaveretum and scopolamine.
进行了一项随机双盲试验,以研究两种常用的术前用药方案及其随后咽痛的发生率。五十名接受常规手术的成年患者在使用吗啡和东莨菪碱或替马西泮进行术前用药后,以标准方式进行麻醉,并在术后接受访谈以评估是否存在咽痛。使用吗啡和东莨菪碱与咽痛发生率显著较高相关。