Kamath B, Curran J, Hawkey C, Beattie A, Gorbutt N, Guiblin H, Kong A
Department of Anaesthesia, City Hospital and Queen's Medical Centre, Nottingham.
Br J Anaesth. 1990 Jun;64(6):728-30. doi: 10.1093/bja/64.6.728.
One hundred and eighty-two women undergoing dilatation and curettage were allocated randomly to receive premedication comprising temazepam, papaveretum-hyoscine or placebo. The temazepam recipients reported significantly fewer episodes of postoperative nausea. Movement was blamed by 66% of patients who identified a cause for nausea. These patients had higher scores on a motion sickness susceptibility questionnaire and were more likely to have been treated previously for nausea or vomiting. It may be possible to identify susceptible patients before surgery.
182名接受刮宫术的女性被随机分配，分别接受含有替马西泮、罂粟碱-东莨菪碱或安慰剂的术前用药。接受替马西泮的患者术后恶心发作次数明显较少。66%确定恶心原因的患者将其归咎于活动。这些患者在晕动病易感性问卷上得分较高，且更有可能曾因恶心或呕吐接受过治疗。或许在手术前就能识别出易患恶心的患者。
