Bush M, Custer R, Smeller J, Bush L M
J Am Vet Med Assoc. 1977 Nov 1;171(9):866-9.
The arterial acid-base balance and other selected physiologic measures of physically restrained and chemically immobilized nonhuman primates from the families Callithricidae, Cebidae, Cercopithecidae, and Pongidae were compared. The physically restrained primates had significantly lower pH, pCO2, and base excess values, but they had significantly higher pO2 values, rectal temperatures, and pulse and respiration rates. Of 56 physically restrained primates, 30 (54%) experienced severe metabolic acidosis, with pH values less than 7.2; 15 (27% of total) had pH values less than 7.1. Two types of behavior were observed during the physical restraint of golden marmosets. Some of the marmosets were excited during restraint, with a great deal of struggling and vocalizing. The other marmosets were quiet and calm, with minimal struggling. The excited group had significantly lower pH, pCO2, and base excess values, but significantly higher pO2 values, rectal temperatures, and pulse and respiration rates. Primates immobilized with ketamine or tiletaminezolazepam had a near normal acid-base balance and were handled more easily than the physically restrained animals.
对绢毛猴科、卷尾猴科、猕猴科和猩猩科中受到身体约束和化学固定的非人灵长类动物的动脉酸碱平衡及其他选定的生理指标进行了比较。受到身体约束的灵长类动物的pH值、二氧化碳分压（pCO2）和碱剩余值显著较低，但它们的氧分压（pO2）值、直肠温度以及脉搏和呼吸频率显著较高。在56只受到身体约束的灵长类动物中，30只（54%）出现了严重代谢性酸中毒，pH值低于7.2；15只（占总数的27%）的pH值低于7.1。在对金狮狨进行身体约束期间观察到两种行为类型。一些狨猴在约束期间很兴奋，挣扎和鸣叫频繁。另一些狨猴则安静平和，挣扎极少。兴奋组的pH值、pCO2和碱剩余值显著较低，但pO2值、直肠温度以及脉搏和呼吸频率显著较高。用氯胺酮或替来他明 - 唑拉西泮固定的灵长类动物的酸碱平衡接近正常，并且比受到身体约束的动物更易于处理。
