静脉注射免疫球蛋白治疗 Sydenham 舞蹈病
Treatment of sydenham chorea with intravenous immunoglobulin.
作者信息
Walker Kathleen, Brink Anita, Lawrenson John, Mathiassen Wendy, Wilmshurst Jo M
机构信息
Rheumatic Fever Clinic, Department of Cardiology, Red Cross Children's Hospital, School of Child and Adolescent Health, University of Cape Town, Cape Town, South Africa.
出版信息
J Child Neurol. 2012 Feb;27(2):147-55. doi: 10.1177/0883073811414058. Epub 2011 Aug 24.
Sydenham chorea is a post-streptococcal, autoimmune, neuropsychiatric, movement disorder. There is no effective treatment. In a randomized study, comparison was made of the outcomes of 10 children treated with standard management alone compared to 10 who received additional intravenous immunoglobulin. The outcomes were assessed using a clinical rating scale, brain single-photon emission computed tomography, and the duration of symptomatic treatment. All three outcome measurement tools found improved outcomes in the group that received intravenous immunoglobulin.
西德纳姆舞蹈病是一种链球菌感染后自身免疫性神经精神运动障碍。目前尚无有效治疗方法。在一项随机研究中，对仅接受标准治疗的10名儿童与另外10名接受静脉注射免疫球蛋白治疗的儿童的治疗结果进行了比较。使用临床评分量表、脑单光子发射计算机断层扫描以及症状治疗持续时间对结果进行评估。所有三种结果测量工具均发现接受静脉注射免疫球蛋白治疗的组治疗效果更好。
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