Dambrain Abel, Boursot Charles, Cohen Tannugi Kévin, Reichart Julien, Lacoeuille Franck
Department of Nuclear Medicine, University Hospital Center, Angers, France.
Department of Nuclear Medicine, Le Mans Hospital Center, Le Mans, France.
Front Nucl Med. 2024 Dec 24;4:1527150. doi: 10.3389/fnume.2024.1527150. eCollection 2024.
Sydenham's chorea is an autoimmune reaction against cerebral basal ganglia associated with rheumatic fever, caused by group A beta-hemolytic streptococcus infection. Diagnosis of this condition is difficult because of significant delay between infection onset and symptoms presentation, resulting in few positive biological tests or imaging exams. We report the case of a nine-year-old boy exhibiting hemicorporal abnormal movements with tics for whom [F]FDG PET/CT exam allowed to make the diagnosis, associated with anti-DNase B elevation. Other biology, spinal tap, EEG and imaging modality like MRI or scanner, were non-contributory.
西德纳姆舞蹈病是一种针对与风湿热相关的大脑基底神经节的自身免疫反应，由A组β溶血性链球菌感染引起。由于感染开始到症状出现之间存在显著延迟，导致很少有阳性生物学检查或影像学检查结果，因此这种疾病的诊断很困难。我们报告了一例9岁男孩的病例，该男孩表现出半身异常运动和抽搐，[F]FDG PET/CT检查使其得以确诊，同时伴有抗脱氧核糖核酸酶B升高。其他生物学检查、腰椎穿刺、脑电图以及MRI或CT等影像学检查均无诊断价值。
