Greiner L, Münks C, Heil W, Jakobeit C
Medical Clinic A, Municipal Hospitals, Wuppertal, Federal Republic of Germany.
Gastroenterology. 1990 Jun;98(6):1620-4. doi: 10.1016/0016-5085(90)91099-r.
All stools passed on the first 3 days after extracorporeal shock-wave lithotripsy of gallbladder stones in 21 patients were collected and examined for the presence of stone fragments. A total of 555 fragments varying in number per patient (4-69) and in size (maximum diameters from 0.5-8.0 mm) were recovered by sieving aqueous suspensions of the feces. All 482 fragments less than or equal to 3.0 mm left the biliary tract without any clinical symptoms, as did the three largest fragments with maximum diameters of 7.0-8.0 mm and almost all of the 70 fragments measuring 3.5-5.0 mm. During the observation period, four episodes of biliary complaints were recorded in three patients in whom fragments with maximum diameters of 3.5-5.0 mm were found. The only chemical abnormality was a temporary elevation of lipase activity to twice the normal range in 1 case. All fragments were identified as gallbladder stones by infrared spectroscopy on the basis of their (varyingly high) cholesterol content. By macroscopic criteria, most of the fragments were from mixed stones; therefore, provided there is a functioning gallbladder and sufficiently fine fragmentation, successful extracorporeal shock-wave lithotripsy does not seem to be limited to pure cholesterol stones.
收集了21例胆囊结石患者在体外冲击波碎石术后头3天排出的所有粪便,检查其中是否存在结石碎片。通过筛分粪便的水悬浮液,共回收了555块碎片,每位患者的碎片数量不同(4 - 69块),大小也不同(最大直径为0.5 - 8.0毫米)。所有482块直径小于或等于3.0毫米的碎片均未引起任何临床症状就离开了胆道,3块最大直径为7.0 - 8.0毫米的碎片以及几乎所有70块直径为3.5 - 5.0毫米的碎片也是如此。在观察期内,3名发现有最大直径为3.5 - 5.0毫米碎片的患者记录了4次胆道不适发作。唯一的化学异常是1例患者的脂肪酶活性暂时升高至正常范围的两倍。通过红外光谱法,根据碎片(胆固醇含量各不相同且较高),所有碎片均被鉴定为胆囊结石。从宏观标准来看,大多数碎片来自混合结石;因此,只要胆囊功能正常且碎石足够细,成功的体外冲击波碎石术似乎并不局限于纯胆固醇结石。