Nii Kouhei, Tsutsumi Masanori, Aikawa Hiroshi, Hamaguchi Shuko, Etou Housei, Sakamoto Kimiya, Kazekawa Kiyoshi
Department of Neurosurgery, Fukuoka University Chikushi Hospital, Chikushino, Fukuoka, Japan.
Neurol Med Chir (Tokyo). 2011;51(8):556-60. doi: 10.2176/nmc.51.556.
The rates of hemodynamic depression (HD) and thromboembolism were compared in 95 carotid artery stenting (CAS) procedures performed in 87 patients with severe carotid artery stenosis using self-expandable braided Elgiloy stents (Wallstent) in 52 and slotted-tube Nitinol stents (Precise) in 43 procedures. The blood pressure, pulse rate, and neurological signs were recorded at short intervals during and after CAS. All patients underwent diffusion-weighted magnetic resonance imaging within 5 days after the procedure. The incidences of hypotension, bradycardia, and both were 17.9%, 3.2%, and 11.6%, respectively. The rate of postprocedural HD was 23.1% with Wallstent and 44.2% with Precise; the difference was significant (p = 0.025). No patient manifested major cardiovascular disease after CAS. Diffusion-weighted magnetic resonance imaging revealed thromboembolism after 26.9% and 34.9% of Wallstent and Precise stent placement procedures, respectively; the difference was not significant. The type of self-expandable stent placed may affect the risk of procedural HD in patients undergoing CAS. Postprocedural HD was resolved successfully by the administration of vasopressors and by withholding antihypertensive agents.
在87例严重颈动脉狭窄患者中进行了95例颈动脉支架置入术(CAS),比较血流动力学抑制(HD)和血栓栓塞的发生率。其中52例使用自膨式编织埃尔吉洛伊合金支架(Wallstent),43例使用开槽管镍钛合金支架(Precise)。在CAS期间及术后短时间间隔记录血压、脉搏率和神经学体征。所有患者在术后5天内接受弥散加权磁共振成像检查。低血压、心动过缓及两者并发的发生率分别为17.9%、3.2%和11.6%。Wallstent术后HD发生率为23.1%,Precise为44.2%;差异有统计学意义(p = 0.025)。CAS术后无患者出现重大心血管疾病。弥散加权磁共振成像显示,Wallstent和Precise支架置入术后血栓栓塞发生率分别为26.9%和34.9%;差异无统计学意义。所置入的自膨式支架类型可能会影响接受CAS患者的术中HD风险。通过给予血管升压药和停用抗高血压药物,术后HD得以成功解决。