Yalcin Selim, Toprak Selami Kocak, Erismis Betul, Altundag Ozden, Ozdemir Handan, Topcuoglu Nuray
Department of Oncology, Baskent University School of Medicine, 06490 Ankara, Turkey.
Case Rep Med. 2011;2011:230840. doi: 10.1155/2011/230840. Epub 2011 Aug 14.
Kikuchi-Fujimoto disease, also known as histiocytic necrotizing lymphadenitis, is a self-limiting, benign, and rare systemic lymphadenitis with unknown etiology. The cardinal symptoms are fever, lymphadenopathy and night sweat; consequently, it is first necessary to rule out infectious, lymphoproliferative, and connective tissue diseases such as systemic lupus erythematosus. Histology can allow diagnosis by demonstrating necrotizing histiocyte lymphadenitis. Disease, which has no specific treatment, self-limits itself in 1 to 6 months clinically. However, non-steroid anti-inflammatory agents can be given for symptomatic treatment and there are reports using corticosteroids and antibiotics in complicated cases. This article concerns a 32-years-old female who diagnosed Kikuchi-Fujimoto disease and treated with glucocorticoid.
菊池-藤本病，又称组织细胞坏死性淋巴结炎，是一种病因不明的自限性、良性且罕见的系统性淋巴结炎。主要症状为发热、淋巴结病和盗汗；因此，首先有必要排除感染性、淋巴增殖性和结缔组织疾病，如系统性红斑狼疮。组织学检查可通过显示坏死性组织细胞性淋巴结炎来确诊。本病无特效治疗方法，临床上1至6个月可自愈。然而，可给予非甾体抗炎药进行对症治疗，也有在复杂病例中使用皮质类固醇和抗生素的报道。本文讲述了一名32岁女性被诊断为菊池-藤本病并接受糖皮质激素治疗的病例。
