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菊池病“一种狼疮模仿者”:病例报告

Kikuchi Disease "A Lupus Mimicker": A Case Report.

作者信息

Alsaadi Aliya Juma, Al Hashmi Saud, Al-Julandani Nabila

机构信息

Dermatology Department, Armed Forces Hospital, Muscat, Oman.

Histopathology Department, Armed Forces Hospital, Muscat, Oman.

出版信息

Oman Med J. 2024 May 30;39(3):e639. doi: 10.5001/omj.2024.21. eCollection 2024 May.

Abstract

Kikuchi disease, also called, Kikuchi-Fujimoto disease or histiocytic necrotizing lymphadenitis, is a rare self-limiting illness with an unknown etiology and pathogenesis. It is predominantly seen among young females. The cardinal clinical features include fever and cervical lymphadenopathy. Skin eruptions have also been reported. In Oman, two cases have been reported to date, in 2005 and 2020, with only one case exhibiting skin manifestations. There is a paucity of disease in our country and worldwide. In this case report, we discuss the diagnosis of Kikuchi disease in a previously healthy 17-year-old Omani female who presented with fever, cervical lymphadenopathy, and malar rash. The clinical picture in this case resembled that of systemic lupus erythematosus. Due to the rarity of Kikuchi disease, particularly in our region, it is crucial to consider it as a differential diagnosis when a patient exhibits the aforementioned symptoms to prevent misdiagnosis and inappropriate treatment, as it can easily be misdiagnosed as systemic lupus erythematosus.

摘要

菊池病,也称为菊池-藤本病或组织细胞坏死性淋巴结炎,是一种病因和发病机制不明的罕见自限性疾病。主要见于年轻女性。主要临床特征包括发热和颈部淋巴结病。也有皮肤疹的报道。在阿曼,迄今为止已报告两例,分别在2005年和2020年,只有一例有皮肤表现。在我国和全世界,这种疾病都很罕见。在本病例报告中,我们讨论了一名此前健康的17岁阿曼女性菊池病的诊断,该患者出现发热、颈部淋巴结病和颧部皮疹。该病例的临床表现类似于系统性红斑狼疮。由于菊池病罕见,尤其是在我们地区,当患者出现上述症状时,将其作为鉴别诊断至关重要,以防止误诊和不恰当的治疗,因为它很容易被误诊为系统性红斑狼疮。

相似文献

1
Kikuchi Disease "A Lupus Mimicker": A Case Report.菊池病“一种狼疮模仿者”:病例报告
Oman Med J. 2024 May 30;39(3):e639. doi: 10.5001/omj.2024.21. eCollection 2024 May.

本文引用的文献

1
Blood cell and marrow changes in patients with Kikuchi disease.菊池病患者的血细胞和骨髓变化
Haematologica. 2022 Aug 1;107(8):1981-1985. doi: 10.3324/haematol.2022.280746.
2
Unilateral Cervical Lymphadenopathy.单侧颈淋巴结病
Oman Med J. 2020 Apr 30;35(2):e121. doi: 10.5001/omj.2020.39. eCollection 2020 Mar.
3
Kikuchi-Fujimoto Disease: A Review.菊池-藤本病:综述。
Arch Pathol Lab Med. 2018 Nov;142(11):1341-1346. doi: 10.5858/arpa.2018-0219-RA.
9
Association of Kikuchi-Fujimoto's disease with SLE.菊池-藤本病与系统性红斑狼疮的关联。
Rheumatology (Oxford). 2008 Apr;47(4):553-4. doi: 10.1093/rheumatology/ken008. Epub 2008 Feb 26.
10
Kikuchi-Fujimoto Disease: analysis of 244 cases.菊池-藤本病:244例分析
Clin Rheumatol. 2007 Jan;26(1):50-4. doi: 10.1007/s10067-006-0230-5. Epub 2006 Mar 15.

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