Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, P.R. China.
Nat Prod Res. 2012;26(15):1408-12. doi: 10.1080/14786419.2011.598155. Epub 2011 Aug 26.
A new triterpenoid glycoside, heterobetulinic acid 3-O-β-D-glucopyranosyl(1 → 2)-β-D-xylopyranoside (1), together with a new phenylacrylic acid derivative, 3'S,4'-dihydroxyl-2'-methylene-but-1'-enyl caffeate (2), were isolated from the roots of Ilex pubescens. Their structures were elucidated by HR-ESI-MS, 1-D and 2-D NMR analyses and chemical methods. In addition, the absolute configuration of 2 was established by the application of a modified Mosher's method.
从毛冬青的根部分离得到了一个新的三萜糖苷，即白桦脂酸 3-O-β-D-吡喃葡萄糖基(1 → 2)-β-D-吡喃木糖苷（1），以及一个新的苯丙烯酸衍生物，3'S,4'-二羟基-2'-亚甲基-丁-1'-烯基咖啡酸酯（2）。它们的结构通过高分辨电喷雾质谱（HR-ESI-MS）、1D 和 2D NMR 分析以及化学方法进行了阐明。此外，通过应用改良的 Mosher 法确定了 2 的绝对构型。
