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基因组民族主义的技术政治:追踪基因组学及其在日本和台湾的药物监管中的应用。

Techno-politics of genomic nationalism: tracing genomics and its use in drug regulation in Japan and Taiwan.

机构信息

National Yang-Ming University, Institute of Science, Technology and Society, No. 155, Sec. 2, Linong Street, Taipei 11221, Taiwan.

出版信息

Soc Sci Med. 2011 Oct;73(8):1200-7. doi: 10.1016/j.socscimed.2011.06.066. Epub 2011 Aug 11.

DOI:10.1016/j.socscimed.2011.06.066
PMID:21871702
Abstract

This paper compares the development of genomics as a form of state project in Japan and Taiwan. Broadening the concepts of genomic sovereignty and bionationalism, I argue that the establishment and use of genomic databases vary according to techno-political context. While both Japan and Taiwan hold population-based databases to be necessary for scientific advance and competitiveness, they differ in how they have attempted to transform the information produced by databases into regulatory schemes for drug approval. The effectiveness of Taiwan's biobank is severely limited by the IRB reviewing process. By contrast, while updating its regulations for drug approval, Japan, is using pharmacogenomics to deal with matters relating to ethnic identity. By analysing genomic initiatives in the political context that nurtures them, this paper seeks to capture how global science and local societies interact and offers insight into the assessment of state-sponsored science in East Asia as they become transnational.

摘要

本文比较了基因组学作为日本和台湾的国家项目的发展。通过拓宽基因组主权和生物民族主义的概念,我认为基因组数据库的建立和使用因技术政治背景而异。虽然日本和台湾都认为基于人群的数据库对于科学进步和竞争力是必要的,但它们在试图将数据库产生的信息转化为药物审批监管方案方面存在差异。台湾生物银行的有效性受到 IRB 审查过程的严重限制。相比之下,日本在更新其药物审批法规的同时,正在利用药物基因组学来处理与种族身份有关的问题。通过分析促进这些基因组计划的政治背景,本文试图捕捉全球科学与当地社会的互动方式,并深入了解东亚国家资助的科学在成为跨国科学时的评估。

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引用本文的文献

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Confidentiality and data sharing: vulnerabilities of the Mexican Genomics Sovereignty Act.保密性与数据共享:墨西哥《基因组主权法案》的漏洞
J Community Genet. 2015 Jul;6(3):313-9. doi: 10.1007/s12687-015-0233-5. Epub 2015 May 20.
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ELSI practices in genomic research in East Asia: implications for research collaboration and public participation.
东亚基因组研究中的伦理、法律和社会问题实践:对研究合作与公众参与的启示
Genome Med. 2014 May 30;6(5):39. doi: 10.1186/gm556. eCollection 2014.