Meyer F, Al Qahtani S, Gil-Diez de Medina S, Geavlete B, Thomas A, Traxer O
Service d'Urologie, Hôpital Tenon, 4 Rue de la Chine, 75020 Paris, France.
Prog Urol. 2011 Sep;21(8):527-33. doi: 10.1016/j.purol.2011.03.002. Epub 2011 May 13.
Endoscopic treatment of upper urinary tract carcinomas (UUTC) is becoming more and more prevalent compared to non-conservative surgery. Our goal was to determine if NBI technology could improve tumour detection.
Twenty-seven patients with known or suspected UUTC were prospectively enrolled and treated using the Olympus URF-V flexible ureteroscope. We report 13 new cases (48%) and 14 known cases as follow up (52%). White light and NBI were subsequently performed to examine the upper urinary tract. Visual aspect of the lesions could be compared using both types of light. Biopsies were taken for all apparent lesions prior to vaporization by Holmium laser.
Forty-three lesions were detected in 21 patients. Five lesions (14.2%) in four patients were detected through NBI light only among the 35 lesions containing UUTC. Two out of four of these patients were new cases and would not have been diagnosed with white light alone. Three UUTC-treated (8.5%) had extended margins in NBI. Thirteen biopsies (26%) were not valid. Altogether, the tumour detection rate improved by 22.7% in seven patients (25.9%) by using the NBI method.
Upper urinary tract endoscopy with NBI light is a new technology that improves visualization of UUCT and enables diagnosis of lesions non visible in white light. This procedure cannot yet be recommended for daily practice and further validation of the technique is required.
与非保守性手术相比,上尿路癌(UUTC)的内镜治疗越来越普遍。我们的目标是确定窄带成像(NBI)技术是否能提高肿瘤检测率。
27例已知或疑似UUTC的患者被前瞻性纳入研究,并使用奥林巴斯URF-V软性输尿管镜进行治疗。我们报告了13例新病例(48%)和14例已知病例作为随访(52%)。随后使用白光和NBI对上尿路进行检查。可以使用两种光比较病变的视觉外观。在钬激光汽化之前,对所有明显病变进行活检。
21例患者中检测到43个病变。在35个包含UUTC的病变中,仅通过NBI光检测到4例患者中的5个病变(14.2%)。这4例患者中有2例是新病例,仅用白光无法诊断。3例接受UUTC治疗的患者(8.5%)在NBI下有切缘扩展。13次活检(26%)无效。总体而言,使用NBI方法使7例患者(25.9%)的肿瘤检测率提高了22.7%。
使用NBI光的上尿路内镜检查是一项新技术,可改善UUCT的可视化,并能诊断白光下不可见的病变。该方法目前尚不推荐用于日常实践,需要对该技术进行进一步验证。