Department of Anesthesia and Intensive Care Medicine, University Hospital Basel, Spitalstrasse 21, CH-4031 Basel, Switzerland.
Transfus Med Rev. 2012 Jan;26(1):1-13. doi: 10.1016/j.tmrv.2011.07.005. Epub 2011 Aug 26.
In the recent years, thromboelastography has become a popular monitoring device for hemostasis and transfusion management in major surgery, trauma, and hemophilia. Thromboelastography is performed in whole blood and assesses the viscoelastic property of clot formation under low shear condition. Thromboelastography can be performed with a variety of activator and inhibitors at different concentrations representing the most important factors for different intervals and clot formation variables reported in multiple studies and algorithms. Furthermore, fibrinogen levels and platelet counts have a major influence on thromboelastographic variables. In addition, differences in patient populations, devices, and preanalytical conditions contribute to some conflicting findings in different studies.
近年来，血栓弹力图已成为大型手术、创伤和血友病中止血和输血管理的一种流行监测设备。血栓弹力图在全血中进行，评估在低剪切条件下形成血凝块的粘弹性特性。血栓弹力图可以使用各种激活剂和抑制剂以不同浓度进行，代表不同研究和算法中报告的不同时间间隔和血凝块形成变量的最重要因素。此外，纤维蛋白原水平和血小板计数对血栓弹力图变量有重大影响。此外，患者人群、设备和分析前条件的差异导致不同研究中存在一些相互矛盾的发现。
