Gynecology and Obstetrics Hospital Luis Castelazo Ayala, Social Security Mexican Institute, Mexico City, Mexico.
Int J Gynaecol Obstet. 2011 Nov;115(2):191-3. doi: 10.1016/j.ijgo.2011.05.030. Epub 2011 Aug 27.
To evaluate the differences in visceral fat between women using tibolone and those not using tibolone.
Sixty-five healthy postmenopausal women were included in the study: 26 who were taking tibolone (2.5 mg/day); and 39 who were not receiving tibolone treatment. Anthropometric measurements were performed, with subcutaneous and visceral fat measured via ultrasound. Differences between the groups were determined via Student t test.
There were no significant differences in age (P=0.796), weight (P=0.256), height (P=0.456), body mass index (P=0.08), waist circumference (P=0.420), or waist-hip ratio (P=0.1) between the groups. Hip circumference was significantly lower in the study group than in the control group (97.7 ± 12.2 cm vs 103 ± 8.1cm; P<0.04). There were no significant differences between the groups in subcutaneous fat measurements (P=0.56). There were significantly lower visceral fat measurements (2.8 ± 1.1cm vs 3.9 ± 1.6 cm; P<0.004) and a significantly lower visceral fat-subcutaneous fat ratio (1.1 ± 0.3 vs 1.5 ± 0.7; P<0.005) in the study group than in the control group.
Postmenopausal women who use tibolone have lower visceral fat measurements than do woman of similar age who do not use tibolone.
评估使用替勃龙和未使用替勃龙的女性之间的内脏脂肪差异。
本研究纳入了 65 名健康的绝经后女性：26 名服用替勃龙（2.5mg/天）；39 名未接受替勃龙治疗。进行了人体测量学测量，通过超声测量皮下脂肪和内脏脂肪。通过学生 t 检验确定组间差异。
两组间年龄（P=0.796）、体重（P=0.256）、身高（P=0.456）、体重指数（P=0.08）、腰围（P=0.420）或腰臀比（P=0.1）无显著差异。研究组的臀围明显低于对照组（97.7±12.2cm 比 103±8.1cm；P<0.04）。两组间的皮下脂肪测量值无显著差异（P=0.56）。研究组的内脏脂肪测量值显著较低（2.8±1.1cm 比 3.9±1.6cm；P<0.004），内脏脂肪-皮下脂肪比值显著较低（1.1±0.3 比 1.5±0.7；P<0.005）。
使用替勃龙的绝经后女性的内脏脂肪测量值低于年龄相似未使用替勃龙的女性。
