Carranza-Lira Sebastián, Muro Ana Mirna Fino, Ortiz Sergio Rosales
UMAE Hospital de Gineco Obstetricia "Luis Castelazo Ayala", Instituto Mexicano del Seguro Social, Mexico City, Mexico.
Prz Menopauzalny. 2015 Jun;14(2):90-6. doi: 10.5114/pm.2015.52048. Epub 2015 Jun 22.
To determine the relationship between skinfolds and visceral fat with vascular reactivity according to body weight, fat distribution and time since menopause in Mexican postmenopausal women.
In postmenopausal women, tricipital, suprailiac and subscapular skinfolds as well as blood pressure were measured, and body mass index (BMI) and waist-hip ratio (WHR) were calculated. Brachial artery Doppler ultrasound at baseline and after the hyperemic stimulus was done and Doppler parameters were assessed. For statistical analysis, Pearson and Spearman correlation analysis, as well as Student t were used.
Sixty-six postmenopausal women were studied; age was 54.5 ± 7.4 years. Skinfold thickness was related with subcutaneous and visceral fat. In all groups, the arterial diameter increased after the hyperemic stimulus among 6.5% and 9% of women. The pulsatility index decreased in the whole group and in those with BMI ≤ 27, WHR ≤ 0.85 and time since menopause ≤ 10 years. Negative correlations were observed between the percentage of change in arterial dilatation and the subscapular skinfold and subcutaneous fat in the whole group and in the subgroups with BMI > 27 and WHR > 0.85.
Skinfolds are indirectly related with visceral fat, and skinfold thickness permit to conclude about impact in endothelial environment.
根据体重、脂肪分布及绝经时间，确定墨西哥绝经后女性皮褶厚度和内脏脂肪与血管反应性之间的关系。
测量绝经后女性的肱三头肌、髂上和肩胛下皮褶厚度以及血压，计算体重指数（BMI）和腰臀比（WHR）。在充血刺激前后进行肱动脉多普勒超声检查，并评估多普勒参数。采用Pearson和Spearman相关分析以及Student t检验进行统计学分析。
共研究了66名绝经后女性；年龄为54.5±7.4岁。皮褶厚度与皮下脂肪和内脏脂肪相关。在所有组中，6.5%至9%的女性在充血刺激后动脉直径增加。全组以及BMI≤27、WHR≤0.85且绝经时间≤10年的女性中，搏动指数降低。在全组以及BMI>27和WHR>0.85的亚组中，观察到动脉扩张变化百分比与肩胛下皮褶厚度和皮下脂肪之间呈负相关。
皮褶厚度与内脏脂肪间接相关，皮褶厚度可用于推断其对内皮环境的影响。
