Luna-Ortiz Kuauhyama, Ortega-Gutierrez Cesar, Dominguez-Malagon Hugo, Mosqueda-Taylor Adalberto
Department of Head and Neck Surgery, Instituto Nacional de Cancerologia, México.
Auris Nasus Larynx. 2012 Jun;39(3):333-6. doi: 10.1016/j.anl.2011.07.014. Epub 2011 Aug 27.
Extraosseous osteosarcoma arising in the head and neck region is an exceptional finding, with a few isolated cases informed in the literature. We report a new case of a large high-grade extraosseous osteosarcoma located in the neck.
A 74 year-old woman with a tumor on the right side of the neck was treated by complete surgical resection. The histopathological diagnosis was osteoblastic extraosseous osteosarcoma. PET-CT scan disclosed no evidence of disease in other areas. Patient received adjuvant radiotherapy and after 3 months of follow-up tumor activity was detected in the cavernous sinus and the patient died of disease one month later.
Extraosseous osteosarcoma in head and neck region is exceptional, and incisional biopsy is the only method to establish a diagnosis and the one to differentiate it from other bone-producing soft tissue tumors. Surgery is the gold standard for treatment of extraosseous osteosarcoma.
头颈部发生的骨外骨肉瘤是一种罕见的发现，文献中仅有少数孤立病例报道。我们报告一例位于颈部的大型高级别骨外骨肉瘤新病例。
一名74岁女性，颈部右侧有肿瘤，接受了完整的手术切除治疗。组织病理学诊断为成骨细胞性骨外骨肉瘤。PET-CT扫描未发现其他部位有疾病迹象。患者接受了辅助放疗，随访3个月后，在海绵窦发现肿瘤活动，患者1个月后死于该疾病。
头颈部骨外骨肉瘤罕见，切开活检是确诊并将其与其他产生骨的软组织肿瘤相鉴别的唯一方法。手术是骨外骨肉瘤治疗的金标准。
